Kcnab2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kcnab2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
MGI:109239

21 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kcnab2^em1(IMPC)Mbp/Kcnab2^em1(IMPC)Mbp C57BL/6NCrl-Kcnab2^em1(IMPC)Mbp/MbpMmucd	abnormal eye morphology	J:211773
	abnormal lymph node morphology	J:211773
	decreased lean body mass	J:211773
	enlarged lymph nodes	J:211773
	hyperactivity	J:211773
	increased grip strength	J:211773
	increased total body fat amount	J:211773
Kcnab2^tm1Kmc/Kcnab2^tm1Kmc B6.129S7-Kcnab2^tm1Kmc	decreased body size	J:106453
	impaired adaptive thermogenesis	J:106453
	premature death	J:106453
	tremors	J:106453
Kcnab2^tm1Kmc/Kcnab2^tm1Kmc involves: 129S6/SvEvTac * 129S7/SvEvBrd	decreased core body temperature	J:106453
	premature death	J:106453
	tremors	J:106453
Kcnab2^tm1Kmc/Kcnab2^tm1Kmc involves: 129S7/SvEvBrd * C57BL/6	abnormal afterhyperpolarization	J:167856
	abnormal learning/memory/conditioning	J:167856
	abnormal nervous system electrophysiology	J:167856
	abnormal spatial learning	J:167856
	normal behavior/neurological phenotype	J:167856
	decreased core body temperature	J:106453
	normal hearing/vestibular/ear phenotype	J:167856
	impaired contextual conditioning behavior	J:167856
	premature death	J:75891
	sporadic seizures	J:75891
	tremors	J:75891
Kcnab2^tm2Mes/Kcnab2^tm2Mes involves: 129S7/SvEvBrd * C57BL/6	normal behavior/neurological phenotype	J:167856
	no abnormal phenotype detected	J:75891

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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