Npas2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Npas2
neuronal PAS domain protein 2
MGI:109232

24 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Npas2^em1(IMPC)Mbp/Npas2^em1(IMPC)Mbp C57BL/6N-Npas2^em1(IMPC)Mbp/MbpMmucd	abnormal heart morphology	J:211773
	abnormal lymph node morphology	J:211773
	abnormal skin morphology	J:211773
	absent optic nerve	J:211773
	decreased lymphocyte cell number	J:211773
	enlarged lymph nodes	J:211773
	increased neutrophil cell number	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	small heart	J:211773
Npas2^tm1Slm/Npas2^tm1Slm B6.129S6-Npas2^tm1Slm	decreased circulating adrenaline level	J:125921
	decreased circulating noradrenaline level	J:125921
	decreased heart rate	J:125921
	decreased mean systemic arterial blood pressure	J:125921
	hypotension	J:125921
Npas2^tm1Slm/Npas2^tm1Slm involves: 129S6/SvEvTac	abnormal blood flow velocity	J:155089
	abnormal circulating protein level	J:155089
	abnormal response to injury	J:155089
Npas2^tm1Slm/Npas2^tm1Slm involves: 129S6/SvEvTac * C57BL/6J	abnormal brain wave pattern	J:109589
	abnormal contextual conditioning behavior	J:63035
	abnormal cued conditioning behavior	J:63035
	abnormal frequency of paradoxical sleep	J:109589
	abnormal learning/memory/conditioning	J:63035
	abnormal sleep duration	J:109589
	abnormal sleep pattern	J:109589

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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