40 phenotypes from 11 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hfetm1.1Gfn/Hfetm1.1Gfn B6.129P2-Hfetm1.1Gfn	abnormal gait	J:114351
	abnormal pilomotor reflex	J:114351
	abnormal postural reflex	J:114351
	decreased body length	J:114351
	impaired coordination	J:114351
	induced hyperactivity	J:114351
	short tail	J:114351
Hfetm1.1Jrco/Hfe+ involves: 129X1/SvJ * C57BL/6J	oxidative stress	J:201948
Hfetm1.1Jrco/Hfetm1.1Jrco involves: 129X1/SvJ * C57BL/6J	abnormal brain iron level	J:201948
	astrocytosis	J:201948
	increased body weight	J:201948
	increased liver iron level	J:201948
	oxidative stress	J:201948
Hfetm1.1Nca/Hfetm1.1Nca involves: 129S6/SvEvTac	abnormal iron level	J:78536
Hfetm1.1Nca/Hfetm1.1Nca involves: 129S6/SvEvTac * C57BL/6J	abnormal iron level	J:78536
Hfetm1.1Nca/Hfetm1.1Nca Not Specified	increased liver iron level	J:62112
Hfetm1.1Wsr/Hfetm1.1Wsr involves: 129P2/OlaHsd * C57BL/6	abnormal iron homeostasis	J:141745
	decreased spleen iron level	J:132134
	hemochromatosis	J:132134
	increased circulating iron level	J:132134, J:132141
	increased liver iron level	J:132134, J:132141, J:141745
Hfetm1Gfn/Hfetm1Gfn involves: 129P2/OlaHsd * C57BL/6	abnormal iron homeostasis	J:68025
	abnormal iron level	J:262906
	abnormal trabecular bone morphology	J:262906
	decreased bone trabecula number	J:262906
	decreased trabecular bone thickness	J:262906
	decreased trabecular bone volume	J:262906
	increased body weight	J:262906
	increased circulating iron level	J:68025
	increased liver iron level	J:68025, J:262906
	increased osteoclast cell number	J:262906
	increased spleen iron level	J:68025
	osteoporosis	J:262906
Hfetm1Sly/Hfetm1Sly Not Specified	increased liver iron level	J:88143
Hfetm1Sly/Hfetm2Sly involves: 129X1/SvJ * C57BL/6J	increased liver iron level	J:88143
Hfetm1Wsr/Hfetm1Wsr Lyz2tm1(cre)Ifo/? involves: 129P2/OlaHsd * C57BL/6	normal homeostasis/metabolism phenotype	J:132134
Hfetm1Wsr/Hfetm1Wsr Tg(Alb1-cre)7Gsc/? involves: 129P2/OlaHsd * C57BL/6 * FVB/N	decreased spleen iron level	J:132134
	hemochromatosis	J:132134
	increased circulating iron level	J:132134
	increased liver iron level	J:132134
Hfetm1Wsr/Hfetm1Wsr Tg(Vil1-cre)997Gum/? involves: 129P2/OlaHsd * C57BL/6 * SJL	no abnormal phenotype detected	J:141745
Hfetm2Nca/Hfe+ involves: 129S6/SvEvTac	increased liver iron level	J:62112
Hfetm2Nca/Hfetm2Nca involves: 129S6/SvEvTac	abnormal iron level	J:78536
	decreased spleen iron level	J:78536
	increased circulating iron level	J:133221
	increased liver iron level	J:62112, J:133221
Hfetm2Nca/Hfetm2Nca involves: 129S6/SvEvTac * C57BL/6J	abnormal iron level	J:78536
	decreased spleen iron level	J:78536
Hfetm2Nca/Hfetm2Nca Tg(Ttr-Hfe)1Nca/0 involves: 129S6/SvEvTac * C57BL/6	decreased circulating iron level	J:133221
	decreased liver iron level	J:133221
	hypochromic microcytic anemia	J:133221
Hfetm2Sly/Hfetm2Sly involves: 129X1/SvJ * C57BL/6J	abnormal brain iron level	J:213886
	abnormal brain size	J:213886
	abnormal object recognition memory	J:213886
	abnormal response to novel object	J:213886
	abnormal spatial reference memory	J:213886
	abnormal spatial working memory	J:213886
	decreased brain cholesterol level	J:213886
	decreased brain weight	J:213886
	decreased corpus callosum size	J:213886
	enlarged brain ventricles	J:213886
	impaired spatial learning	J:213886
	increased liver iron level	J:88143
	neuron degeneration	J:213886
Hfetm2Sly/Hfetm3Sly involves: 129X1/SvJ * C57BL/6J	increased liver iron level	J:88143
Hfetm3Sly/Hfetm3Sly involves: 129X1/SvJ * C57BL/6J	increased liver iron level	J:88143