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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fzd5
frizzled class receptor 5
MGI:108571
35 phenotypes from 5 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fzd5tm1.1(KOMP)Vlcg/Fzd5+
C57BL/6N-Fzd5tm1.1(KOMP)Vlcg/Ucd 		abnormal heart morphology J:211773
enlarged heart J:211773
hydrometra J:211773
small superior vagus ganglion J:211773
Fzd5tm1.1(KOMP)Vlcg/Fzd5tm1.1(KOMP)Vlcg
C57BL/6N-Fzd5tm1.1(KOMP)Vlcg/Ucd 		preweaning lethality, complete penetrance J:211773
Fzd5tm1Cle/Fzd5tm1Cle
involves: 129P2/OlaHsd 		ectopic Paneth cells J:98680
Fzd5tm1Cle/Fzd5tm1Cle
Tg(Six3-cre)69Frty/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 		normal vision/eye phenotype J:136314
Fzd5tm1Mmt/Fzd5tm1Cle
Tg(Six3-cre)69Frty/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * DBA/2 		abnormal eye physiology J:142601
abnormal retina apoptosis J:142601
abnormal retina layer morphology J:142601
abnormal vascular regression J:142601
disorganized retina ganglion layer J:142601
increased cornea thickness J:142601
increased total retina thickness J:142601
microphthalmia J:142601
retina detachment J:142601
retina fold J:142601
small lens J:142601
normal vision/eye phenotype J:142601
vitreous body deposition J:142601
Fzd5tm1Mmt/Fzd5tm1Mmt
involves: 129X1/SvJ 		abnormal eye physiology J:136314
abnormal lens development J:136314
abnormal optic cup morphology J:136314
abnormal optic vesicle formation J:136314
increased retina apoptosis J:136314
Fzd5tm1Mmt/Fzd5tm1Mmt
involves: 129X1/SvJ * C57BL/6 		abnormal placental labyrinth vasculature morphology J:52605
abnormal visceral yolk sac morphology J:52605
abnormal vitelline vascular remodeling J:52605
disorganized yolk sac vascular plexus J:52605
hemorrhage J:52605
pale yolk sac J:52605
prenatal lethality, complete penetrance J:52605
Fzd5tm1Nat/Fzd5tm1Nat
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		prenatal lethality, complete penetrance J:136390
Fzd5tm1Nat/Fzd5tm2Nat
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL 		abnormal thalamus morphology J:136390
decreased body size J:136390
decreased body weight J:136390
impaired coordination J:136390
retina degeneration J:136390
Fzd5tm1Nat/Fzd5tm2Nat
Gt(ROSA)26Sortm1(cre/ERT)Nat/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL 		abnormal thalamus morphology J:136390
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory