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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Fzd4
frizzled class receptor 4
MGI:108520
57 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Fzd4tm1.1(KOMP)Vlcg/Fzd4+
C57BL/6N-Fzd4tm1.1(KOMP)Vlcg/Ucd
abnormal eye morphology J:211773
abnormal eye size J:211773
hydrops fetalis J:211773
microphthalmia J:211773
Fzd4tm1.1(KOMP)Vlcg/Fzd4tm1.1(KOMP)Vlcg
C57BL/6N-Fzd4tm1.1(KOMP)Vlcg/Ucd
hydrops fetalis J:211773
preweaning lethality, incomplete penetrance J:211773
Fzd4tm1.1Lex/Fzd4tm1.1Lex
involves: 129S5/SvEvBrd * C57BL/6
normal cardiovascular system phenotype J:181399
decreased angiogenesis J:181399
Fzd4tm1Nat/Fzd4tm1Nat
involves: 129S1/Sv * 129X1/SvJ
abnormal brain vasculature morphology J:154020
abnormal cerebellum morphology J:154020
abnormal eye electrophysiology J:154020
abnormal optokinetic reflex J:154020
abnormal retinal vasculature morphology J:154020
impaired pupillary reflex J:154020
small kidney J:170839
Fzd4tm1Nat/Fzd4tm1Nat
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal astrocyte physiology J:70078
abnormal cerebellar granule layer morphology J:70078
abnormal cerebellum morphology J:107732
abnormal corpus luteum morphology J:115734
abnormal digestion J:70078
abnormal esophageal squamous epithelium morphology J:70078
abnormal esophagus morphology J:70078
abnormal gait J:70078
abnormal organ of Corti morphology J:107732
abnormal posture J:70078
abnormal retinal vasculature morphology J:107732
abnormal stria vascularis morphology J:107732
abnormal stria vascularis vasculature morphology J:107732
abnormal vascular development J:115734
absent corpus luteum J:115734
absent startle reflex J:70078
ataxia J:70078
cerebellum hypoplasia J:70078
cochlear hair cell degeneration J:107732
cochlear inner hair cell degeneration J:107732
cochlear outer hair cell degeneration J:107732
decreased circulating progesterone level J:115734
decreased Purkinje cell number J:70078
decreased skeletal muscle fiber diameter J:70078
decreased startle reflex J:70078
diluted coat color J:70078
enlarged esophagus J:70078
failure of embryo implantation J:115734
female infertility J:115734
hemorrhage J:107732
hunched posture J:70078
impaired hearing J:70078
impaired luteal cell differentiation J:115734
impaired luteinization J:115734
increased or absent threshold for auditory brainstem response J:70078
male infertility J:115734
persistence of hyaloid vascular system J:107732
premature death J:70078
normal reproductive system phenotype J:115734
retinal hemorrhage J:107732
short stride length J:70078
stria vascularis degeneration J:107732
weight loss J:70078
Fzd4tm1Nat/Fzd4tm2.1Nat
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+
involves: 129S1/Sv * 129X1/SvJ
small kidney J:170839
Fzd4tm1Nat/Fzd4tm2.1Nat
Tg(rx3-icre)1Mjam/?
involves: 129S1/Sv * 129X1/SvJ
abnormal eye electrophysiology J:154020
Fzd4tm1Nat/Fzd4tm2.1Nat
Tg(Tek-cre)1Ywa/0
involves: 129S1/Sv * 129X1/SvJ
normal renal/urinary system phenotype J:170839
Fzd4tm1Nat/Fzd4tm2.1Nat
Tg(Tek-cre)1Ywa/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
abnormal brain vasculature morphology J:154020
abnormal eye electrophysiology J:154020
abnormal optokinetic reflex J:154020
abnormal retinal vasculature morphology J:154020
impaired pupillary reflex J:154020
Fzd4tm2.1Nat/Fzd4tm2.1Nat
involves: 129S1/Sv * 129X1/SvJ
no abnormal phenotype detected J:154020

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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory