Fzd3 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fzd3
frizzled class receptor 3
MGI:108476

20 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Fzd3^tm1(FZD3)Lex/Fzd3^tm1(FZD3)Lex involves: 129S5/SvEvBrd * C57BL/6J	normal cellular phenotype	J:185566
	decreased depression-related behavior	J:185566
	decreased prepulse inhibition	J:185566
	dilated lateral ventricle	J:185566
	dilated third ventricle	J:185566
	normal growth/size/body region phenotype	J:185566
	impaired cued conditioning behavior	J:185566
	reduced sensorimotor gating	J:185566
Fzd3^tm1Nat/Fzd3⁺ Fzd6^tm1Nat/Fzd6^tm1Nat involves: 129S1/Sv * 129X1/SvJ * C57BL/6	oligozoospermia	J:105752
	reduced male fertility	J:105752
Fzd3^tm1Nat/Fzd3^tm1Nat Fzd6^tm1Nat/Fzd6^tm1Nat involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cochlea morphology	J:105752
	abnormal cochlear outer hair cell morphology	J:105752
	abnormal crista ampullaris morphology	J:105752
	abnormal orientation of inner hair cell stereociliary bundles	J:105752
	abnormal tectorial membrane morphology	J:105752
	curly tail	J:105752
	eyelids open at birth	J:105752
	normal hearing/vestibular/ear phenotype	J:105752
	neonatal lethality, complete penetrance	J:105752
	open neural tube	J:105752

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23