Fzd3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fzd3
frizzled class receptor 3
MGI:108476

24 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fzd3^{tm1b(EUCOMM)Hmgu}/Fzd3⁺ C57BL/6N-Fzd3^{tm1b(EUCOMM)Hmgu}/H	decreased bone mineral content	J:211773
	decreased grip strength	J:211773
	impaired glucose tolerance	J:211773
	increased total body fat amount	J:211773
Fzd3^{tm1b(EUCOMM)Hmgu}/Fzd3^{tm1b(EUCOMM)Hmgu} C57BL/6N-Fzd3^{tm1b(EUCOMM)Hmgu}/H	preweaning lethality, incomplete penetrance	J:211773
Fzd3^tm1Nat/Fzd3^tm1Nat involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal breathing pattern	J:79213
	abnormal hindlimb morphology	J:79213
	abnormal lung morphology	J:79213
	abnormal nervous system tract morphology	J:79213
	abnormal spinal cord morphology	J:86902
	abnormal striatum morphology	J:79213
	abnormal telencephalon morphology	J:79213
	abnormal vocalization	J:79213
	absent anterior commissure	J:79213
	absent brain internal capsule	J:86902
	curly tail	J:79213
	cyanosis	J:79213
	decreased corpus callosum size	J:79213
	decreased striatum size	J:79213
	enlarged lateral ventricles	J:79213
	incomplete rostral neuropore closure	J:79213
	neonatal lethality, complete penetrance	J:79213
	thin cerebral cortex	J:79213
Fzd3^tm2.1Nat/Fzd3^tm2.1Nat involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:101977

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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