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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Acaca
acetyl-Coenzyme A carboxylase alpha
MGI:108451
24 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Acacatm1.1Jkus/Acacatm1.1Jkus
involves: 129X1/SvJ * C57BL/6J
embryonic growth retardation J:118861
embryonic lethality during organogenesis J:118861
Acacatm1Dejs/Acacatm1Dejs
Tg(Cd4-cre)1Cwi/?
involves: C57BL/6 * DBA/2
abnormal lipid metabolism J:209886
abnormal T cell physiology J:209886
decreased memory T cell number J:209886
decreased T cell number J:209886
normal immune system phenotype J:209886
Acacatm1Jkus/Acacatm1Jkus
Tg(Fabp1-cre)1Mmt/0
involves: 129X1/SvJ * C57BL/6J * SJL
abnormal lipid homeostasis J:118861
decreased liver triglyceride level J:118861
increased circulating aspartate transaminase level J:118861
Acacatm1Sjw/Acacatm1Sjw
involves: 129S7/SvEvBrd * C57BL/6J
decreased embryo size J:101150
embryonic growth arrest J:101150
embryonic lethality between implantation and somite formation, complete penetrance J:101150
Acacatm2Sjw/Acacatm2Sjw
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129S7/SvEvBrd * C57BL/6J * FVB
abnormal enzyme/coenzyme activity J:110200
abnormal glucose homeostasis J:110200
abnormal lipid level J:110200
abnormal liver physiology J:110200
decreased circulating free fatty acid level J:110200
decreased circulating ketone body level J:110200
decreased fatty acid level J:110200
decreased liver triglyceride level J:110200
decreased susceptibility to hepatic steatosis J:110200
hyperglycemia J:110200
increased circulating free fatty acid level J:110200
increased circulating insulin level J:110200

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory