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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Snrk
SNF related kinase
MGI:108104
37 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Snrktm1.1Hxu/Snrktm1.1Hxu
Tg(Adipoq-cre)1Evdr/0
B6.Cg-Snrktm1.1Hxu Tg(Adipoq-cre)1Evdr 		abnormal adipose tissue distribution J:257980
abnormal circulating chemokine level J:257980
brown adipose tissue inflammation J:257980
decreased core body temperature J:257980
decreased energy expenditure J:257980
decreased fat cell size J:257980
hepatic steatosis J:257980
impaired glucose tolerance J:257980
increased body weight J:257980
increased circulating free fatty acids level J:257980
increased circulating interleukin-6 level J:257980
increased circulating triglyceride level J:257980
increased circulating tumor necrosis factor level J:257980
insulin resistance J:257980
white adipose tissue inflammation J:257980
Snrktm1Hxu/Snrk+
C57BL/6-Snrktm1Hxu 		abnormal brown fat cell morphology J:257980
abnormal white fat cell morphology J:257980
decreased brown fat cell size J:257980
decreased subcutaneous adipose tissue amount J:257980
decreased triglyceride level J:257980
decreased white adipose tissue amount J:257980
increased circulating glucose level J:257980
slow postnatal weight gain J:257980
Snrktm1Hxu/Snrktm1Hxu
C57BL/6-Snrktm1Hxu 		decreased circulating glucose level J:257980
postnatal lethality J:257980
Snrktm1Rra/Snrktm1Rra
involves: C57BL/6J 		abnormal lipid level J:218247
normal cardiovascular system phenotype J:218247
decreased circulating free fatty acids level J:218247
decreased circulating triglyceride level J:218247
enlarged heart J:218247
increased circulating cholesterol level J:218247
increased heart left ventricle size J:218247
neonatal lethality, complete penetrance J:218247
Snrktm2Rra/Snrk+
Tg(Myh6-cre)2182Mds/0
involves: C57BL/6J * FVB/N 		premature death J:218247
Snrktm2Rra/Snrktm2Rra
Tg(Myh6-cre)2182Mds/0
involves: C57BL/6J * FVB/N 		abnormal heart left ventricle morphology J:218247
abnormal lipid level J:218247
normal cardiovascular system phenotype J:218247
decreased ventricle muscle contractility J:218247
normal mortality/aging J:218247
premature death J:218247
Snrktm2Rra/Snrktm2Rra
Tg(Tek-cre)1Ywa/0
involves: C57BL/6 * C57BL/6J * SJL 		normal mortality/aging J:218247
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory