Gab1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gab1
growth factor receptor bound protein 2-associated protein 1
MGI:108088

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cd44^tm1Mak/Cd44^tm1Mak Gab1^tm1Wbm/Gab1⁺ involves: 129P2/OlaHsd * C57BL/6	lethality, incomplete penetrance	J:128984
	neonatal lethality, incomplete penetrance	J:128984
Cxcr4^tm1Qma/Cxcr4^tm1Qma Gab1^tm1Wbm/Gab1^tm1Wbm involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6	abnormal intrinsic tongue muscle morphology	J:100909
	abnormal muscle precursor cell migration	J:100909
	abnormal myogenesis	J:100909
	decreased tongue size	J:100909
	hypaxial muscle hypoplasia	J:100909
Gab1^tm1Nmoc/Gab1^tm1Nmoc Gab2^tm1Thir/Gab2^tm1Thir Tg(Myh6-cre)2182Mds/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N	abnormal cardiac muscle relaxation	J:124033
	abnormal endocardium morphology	J:124033
	abnormal heart left ventricle morphology	J:124033
	abnormal heart morphology	J:124033
	congestive heart failure	J:124033
	decreased cardiac muscle contractility	J:124033
	dilated heart	J:124033
	increased heart weight	J:124033
	increased left ventricle diastolic pressure	J:124033
	premature death	J:124033
	thin interventricular septum	J:124033
Gab1^tm1Wbm/Gab1^tm1Wbm Met^tm1Cbm/Met^tm1Cbm involves: 129P2/OlaHsd * C57BL/6	hypaxial muscle hypoplasia	J:68751
Gab1^tm3Wbm/Gab1^tm3Wbm Met^tm1Cbm/Met⁺ involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * CD-1	cleft secondary palate	J:125303

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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