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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ccna2
cyclin A2
MGI:108069
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ccna1tm1Djw/Ccna1tm1Djw
Ccna2tm1.1Pisc/Ccna2tm1.1Pisc
involves: 129S7/SvEvBrd 		abnormal cell cycle J:155178
abnormal definitive hematopoiesis J:155178
abnormal hematopoietic system physiology J:155178
decreased cell proliferation J:155178
Ccna1tm1Djw/Ccna1tm1Djw
Ccna2tm1.1Pisc/Ccna2tm1.1Pisc
Tg(Mx1-cre)1Cgn/0
involves: 129S7/SvEvBrd * C57BL/6 * CBA 		anemia J:155178
decreased bone marrow cell number J:155178
decreased common myeloid progenitor cell number J:155178
decreased erythrocyte cell number J:155178
decreased erythroid progenitor cell number J:155178
decreased hematopoietic stem cell number J:155178
decreased leukocyte cell number J:155178
premature death J:155178
thrombocytopenia J:155178
Ccna1tm1Djw/Ccna1tm1Djw
Ccna2tm1.1Pisc/Ccna2tm1.2Pisc
involves: 129S4/SvJaeSor * 129S7/SvEvBrd 		decreased cell proliferation J:155178
Tg(Myh6-Ccna2)58Djw/0
involves: C57BL/6 * CBA 		abnormal myocardial fiber morphology J:92551
decreased cardiac muscle contractility J:92551
decreased myocardial fiber size J:92551
enlarged heart J:92551
heart hyperplasia J:92551
increased heart weight J:92551
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory