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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Stx2
syntaxin 2
MGI:108059
27 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Stx2repro34/Stx2repro34
involves: C3HeB/FeJ * C57BL/6J
arrest of male meiosis J:92463, J:136575
arrest of spermatogenesis J:136575
azoospermia J:92463, J:136575
decreased seminal vesicle weight J:92463
decreased testis weight J:92463
male infertility J:92463, J:136575
multinucleated giant male germ cells J:136575
small testis J:136575
Stx2tm1b(EUCOMM)Wtsi/Stx2tm1b(EUCOMM)Wtsi
C57BL/6N-Stx2tm1b(EUCOMM)Wtsi/J
decreased mean corpuscular hemoglobin J:211773
decreased mean corpuscular hemoglobin concentration J:211773
decreased mean corpuscular volume J:211773
increased circulating cholesterol level J:211773
increased circulating HDL cholesterol level J:211773
increased erythrocyte cell number J:211773
male infertility J:211773
Stx2tm1Dcru/Stx2+
involves: 129X1/SvJ * C57BL/6J
abnormal small intestinal crypt cell proliferation J:110376
abnormal small intestinal villus morphology J:110376
abnormal small intestine crypts of Lieberkuhn morphology J:110376
Stx2tm1Dcru/Stx2tm1Dcru
involves: 129X1/SvJ
normal hematopoietic system phenotype J:189176
Stx2tm1Dcru/Stx2tm1Dcru
involves: 129X1/SvJ * C57BL/6J
abnormal seminiferous tubule morphology J:110376
abnormal small intestinal crypt cell proliferation J:110376
abnormal small intestinal villus morphology J:110376
abnormal small intestine crypts of Lieberkuhn morphology J:110376
abnormal spermatogenesis J:110376
azoospermia J:110376
branched small intestinal villi J:110376
decreased litter size J:110376
decreased susceptibility to induced colitis J:110376
decreased testis weight J:110376
increased colon length J:110376
increased liver weight J:110376
increased male germ cell apoptosis J:110376
increased small intestine length J:110376
male infertility J:110376

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory