113 phenotypes from 8 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Atrtm1.1Twgl/Atrtm1.1Twgl involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL	no abnormal phenotype detected	J:150723
Atrtm1Akl/Atr+ involves: 129P2/OlaHsd * C57BL/6	normal neoplasm	J:61732
Atrtm1Akl/Atrtm1Akl involves: 129P2/OlaHsd * C57BL/6	embryonic lethality between implantation and somite formation, complete penetrance	J:61732
Atrtm1b(KOMP)Wtsi/Atr+ B6N(Cg)-Atrtm1b(KOMP)Wtsi/2J	abnormal spinal cord morphology	J:211773
	decreased circulating glucose level	J:211773
	increased heart weight	J:211773
Atrtm1b(KOMP)Wtsi/Atrtm1b(KOMP)Wtsi B6N(Cg)-Atrtm1b(KOMP)Wtsi/2J	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Atrtm1Bal/Atr+ involves: 129 * C57BL/6	increased tumor incidence	J:60768
	premature death	J:60768
Atrtm1Bal/Atrtm1Bal involves: 129 * C57BL/6	embryonic lethality between implantation and somite formation, complete penetrance	J:60768
Atrtm1Bal/Atrtm2Bal Ndor1Tg(UBC-cre/ERT2)1Ejb/0 involves: 129S/SvEv * 129S2/SvPas * C57BL/6	abnormal coat/hair pigmentation	J:123200
	abnormal hair cycle	J:123200
	abnormal hair follicle development	J:123200
	abnormal hair follicle morphology	J:123200
	abnormal hair growth	J:123200
	abnormal hair shaft morphology	J:123200
	abnormal intestinal epithelium morphology	J:123200
	abnormal liver morphology	J:123200
	abnormal thymus involution	J:123200
	abnormal trabecular bone morphology	J:123200
	alopecia	J:123200
	cardiac fibrosis	J:123200
	decreased body weight	J:123200
	decreased cell proliferation	J:123200
	decreased compact bone thickness	J:123200
	decreased hair follicle number	J:123200
	decreased subcutaneous adipose tissue amount	J:123200
	decreased thymocyte number	J:123200
	delayed hair regrowth	J:123200
	kidney atrophy	J:123200
	kidney inflammation	J:123200
	kyphosis	J:123200
	osteoporosis	J:123200
	renal fibrosis	J:123200
	renal glomerulus atrophy	J:123200
	renal tubule atrophy	J:123200
	sebaceous gland hyperplasia	J:123200
	thick skin	J:123200
Atrtm1Bal/Atrtm2Bal Tg(Syn1-cre)671Jxm/0 involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * CBA	normal behavior/neurological phenotype	J:123200
Atrtm1Ofc/Atrtm1Ofc involves: 129 * C57BL/6	abnormal female meiosis	J:307570
	abnormal ovarian follicle morphology	J:307570
	decreased granulosa cell proliferation	J:307570
	decreased primary ovarian follicle number	J:307570
	decreased secondary ovarian follicle number	J:307570
	impaired ovarian folliculogenesis	J:307570
	increased granulosa cell apoptosis	J:307570
	increased granulosa cell proliferation	J:307570
	increased primordial ovarian follicle number	J:307570
Atrtm1Ofc/Atrtm1Ofc Not Specified	abnormal astrocyte morphology	J:151542
	abnormal bone marrow morphology	J:151542
	abnormal brain morphology	J:151542
	abnormal cell cycle	J:151542
	abnormal coat/hair pigmentation	J:151542
	abnormal cranial suture morphology	J:151542
	abnormal DNA replication	J:151542
	abnormal fontanelle morphology	J:151542
	abnormal head shape	J:151542
	abnormal head size	J:151542
	abnormal hematopoietic stem cell morphology	J:151542
	abnormal nose morphology	J:151542
	abnormal oogenesis	J:151542
	abnormal placenta morphology	J:151542
	abnormal primary ovarian follicle morphology	J:151542
	absent corpus callosum	J:151542
	absent oocytes	J:151542
	cachexia	J:151542
	decreased body length	J:151542
	decreased body weight	J:151542
	decreased bone marrow cell number	J:151542
	decreased brain size	J:151542
	decreased brain weight	J:151542
	decreased hair follicle number	J:151542
	decreased liver weight	J:151542
	decreased lung weight	J:151542
	decreased ovary weight	J:151542
	decreased spleen weight	J:151542
	decreased testis weight	J:151542
	decreased thymus weight	J:151542
	early cellular replicative senescence	J:151542
	increased apoptosis	J:151542
	increased cellular sensitivity to methylmethanesulfonate	J:151542
	increased cellular sensitivity to ultraviolet irradiation	J:151542
	increased fibroblast apoptosis	J:151542
	kyphosis	J:151542
	malocclusion	J:151542
	microcephaly	J:151542
	micrognathia	J:151542
	osteoporosis	J:151542
	pancytopenia	J:151542
	premature aging	J:151542
	premature death	J:151542
	prenatal lethality, incomplete penetrance	J:151542
	proportional dwarf	J:151542
	sloping forehead	J:151542
	small thoracic cavity	J:151542
	spontaneous chromosome breakage	J:151542
	thin epidermis	J:151542
Atrtm1Twgl/Atr+ involves: 129S6/SvEvTac * C57BL/6J	decreased mitotic index	J:150723
	induced chromosome breakage	J:150723
Atrtm1Twgl/Atrtm1Twgl involves: 129S6/SvEvTac * C57BL/6J	decreased mitotic index	J:150723
	induced chromosome breakage	J:150723
Atrtm2Bal/Atrtm2Bal Emx1tm1(cre)Krj/Emx1+ involves: 129S2/SvPas * C57BL/6J	abnormal cerebral cortex morphology	J:181920
	abnormal corpus callosum morphology	J:181920
	abnormal stratification in cerebral cortex	J:181920
	hippocampus hypoplasia	J:181920
Atrtm2Bal/Atrtm2Bal Tg(CAG-cre/Esr1*)5Amc/0 involves: 129S2/SvPas * C57BL/6 * CBA	abnormal neuron proliferation	J:181920
Atrtm2Bal/Atrtm2Bal Tg(Nes-cre)1Kln/0 involves: 129S2/SvPas * C57BL/6 * SJL	abnormal cerebellar granule layer morphology	J:181920
	abnormal cerebellum development	J:181920
	abnormal cerebral cortex morphology	J:181920
	abnormal corpus callosum morphology	J:181920
	abnormal embryonic/fetal subventricular zone morphology	J:181920
	abnormal neuron proliferation	J:181920
	abnormal olfactory bulb granule cell layer morphology	J:181920
	abnormal rhombic lip morphology	J:181920
	decreased body size	J:181920
	decreased brain size	J:181920
	decreased cerebellar granule cell number	J:181920
	decreased cerebellar granule cell precursor proliferation	J:181920
	ectopic Purkinje cell	J:181920
	increased neuron apoptosis	J:181920
	postnatal growth retardation	J:181920
	postnatal lethality, complete penetrance	J:181920
Atrtm2Ofc/Atrtm2Ofc Not Specified	normal craniofacial phenotype	J:151542
	normal growth/size/body region phenotype	J:151542