About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Aldh1a2
aldehyde dehydrogenase family 1, subfamily A2
MGI:107928
92 phenotypes from 6 alleles in 8 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Aldh1a2grim/Aldh1a2grim
involves: 129S1/Sv * C57BL/6
abnormal embryo turning J:185330
abnormal first pharyngeal arch morphology J:185330
abnormal heart tube morphology J:185330
abnormal otic vesicle morphology J:185330
abnormal pharyngeal arch morphology J:185330
abnormal vitamin A metabolism J:185330
absent forelimb buds J:185330
absent pharyngeal arches J:185330
decreased somite size J:185330
embryonic growth arrest J:185330
embryonic lethality during organogenesis, complete penetrance J:185330
failure of heart looping J:185330
small first pharyngeal arch J:185330
small forelimb buds J:185330
small otic vesicle J:185330
Aldh1a2grim/Aldh1a2grim
involves: 129S1/Sv * C57BL/6 * FVB/NJ
abnormal glossopharyngeal ganglion morphology J:171522
abnormal mandibular prominence morphology J:171522
abnormal maxillary prominence morphology J:171522
abnormal nervous system development J:171522
abnormal trigeminal ganglion morphology J:171522
abnormal vagus ganglion morphology J:171522
abnormal vascular development J:171522
abnormal vestibulocochlear ganglion morphology J:171522
absent fourth pharyngeal arch J:171522
absent pharyngeal arch arteries J:171522
absent third pharyngeal arch J:171522
decreased embryo size J:171522
embryonic lethality during organogenesis, complete penetrance J:171522
Aldh1a2tm1Dll/Aldh1a2tm1Dll
Not Specified
aberrant origin of the right subclavian artery J:81969
abnormal aortic arch and aortic arch branch attachment J:81969
abnormal artery morphology J:81969
abnormal common carotid artery morphology J:81969
abnormal left subclavian artery morphology J:81969
abnormal truncus arteriosus septation J:81969
cervical aortic arch J:81969
cyanosis J:81969
decreased body size J:81969
decreased tracheal cartilage ring number J:81969
postnatal lethality, incomplete penetrance J:81969
short trachea J:81969
Aldh1a2tm1Dll/Aldh1a2tm1Ipc
involves: CD-1
aberrant origin of the right subclavian artery J:81969
abnormal artery morphology J:81969
abnormal common carotid artery morphology J:81969
abnormal cranial nerve morphology J:81969
abnormal cricoid cartilage morphology J:81969
abnormal laryngeal cartilage morphology J:81969
abnormal left subclavian artery morphology J:81969
abnormal neural crest cell migration J:81969
abnormal pharyngeal arch artery morphology J:81969
abnormal pharyngeal pouch morphology J:81969
abnormal third pharyngeal arch artery morphology J:81969
abnormal thyroid cartilage morphology J:81969
abnormal tracheal cartilage morphology J:81969
absent parathyroid glands J:81969
absent third pharyngeal arch J:81969
athymia J:81969
conotruncal ridge hypoplasia J:81969
cyanosis J:81969
decreased body size J:81969
double aortic arch J:81969
fusion of glossopharyngeal and vagus nerve J:81969
persistent truncus arteriosis J:81969
pharyngeal arch hypoplasia J:81969
postnatal lethality, complete penetrance J:81969
right aortic arch J:81969
short trachea J:81969
thymus hypoplasia J:81969
ventricular septal defect J:81969
Aldh1a2tm1Dll/Aldh1a2tm1Ipc
Tg(Rarb-cre)1Mrc/0
Not Specified
abnormal digit morphology J:97213
abnormal motor neuron innervation pattern J:97213
normal muscle phenotype J:97213
normal skeleton phenotype J:97213
syndactyly J:97213
Aldh1a2tm1Gdu/Aldh1a2tm1Gdu
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal heart development J:75950
absent second pharyngeal arch J:75950
absent third pharyngeal arch J:75950
decreased body length J:75950
decreased embryo size J:75950
decreased somite size J:75950
embryonic lethality during organogenesis, complete penetrance J:75950
failure of heart looping J:75950
small otic vesicle J:75950
Aldh1a2tm1Gdu/Aldh1a2tm1Gdu
involves: 129S1/Sv * 129X1/SvJ * Swiss Webster
renal hypoplasia J:157254
Aldh1a2tm1Gdu/Aldh1a2tm1Gdu
Tg(Hoxb7-EGFP)33Cos/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * Swiss Webster
impaired branching involved in ureteric bud morphogenesis J:157254
Aldh1a2tm1Ipc/Aldh1a2tm1Ipc
Not Specified
abnormal embryo turning J:54067
abnormal embryonic tissue morphology J:54067
abnormal fetal atrioventricular canal morphology J:67816
abnormal fetal cardiomyocyte morphology J:67816
abnormal heart development J:54067, J:67816
abnormal myocardium layer morphology J:67816
abnormal neural tube morphology J:54067
abnormal pharyngeal arch morphology J:54067
abnormal somite development J:54067
abnormal vitelline vasculature morphology J:54067
absent atrioventricular cushions J:67816
absent hindlimb buds J:54067
absent myocardial trabeculae J:54067
absent Wolffian ducts J:54067
caudal body truncation J:54067
decreased embryo size J:54067
decreased somite size J:54067
embryonic lethality during organogenesis, complete penetrance J:54067
enlarged heart J:54067
failure of heart looping J:54067, J:67816
failure of ventral body wall closure J:54067
incomplete caudal neuropore closure J:54067
otic vesicle hypoplasia J:54067
small frontonasal prominence J:54067
thick myocardium J:67816
Aldh1a2tm1Soc/Aldh1a2tm1Soc
Not Specified
embryonic lethality, complete penetrance J:112635
Aldh1a2tm1Soc/Aldh1a2tm2Soc
Not Specified
no abnormal phenotype detected J:112635
Aldh1a2tm1Soc/Aldh1a2tm2Soc
Isl1tm1(cre)Tmj/Isl1+
involves: 129X1/SvJ
abnormal motor neuron innervation pattern J:112635
decreased motor neuron number J:112635
Aldh1a2tm1Soc/Aldh1a2tm2Soc
Tg(Dll1-cre)1Gos/0
Not Specified
abnormal motor neuron innervation pattern J:112635
abnormal vitamin A level J:112635
decreased motor neuron number J:112635
normal limbs/digits/tail phenotype J:112635

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/13/2019
MGI 6.14
The Jackson Laboratory