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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Has2
hyaluronan synthase 2
MGI:107821
51 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Has2tm1.1Chg/Has2tm1.1Chg
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J
abnormal mandible morphology J:283393
abnormal maxilla morphology J:283393
abnormal Meckel's cartilage morphology J:283393
abnormal oral cavity morphology J:283393
abnormal palate development J:283393
complete cleft palate J:283393
decreased palatal shelf size J:283393
failure of palatal shelf elevation J:283393
increased tongue size J:283393
micrognathia J:283393
neonatal lethality, complete penetrance J:283393
protruding tongue J:283393
short mandible J:283393
short Meckel's cartilage J:283393
Has2tm1.1Chg/Has2tm1.2Chg
Tg(Hoxb6-cre)#Mku/0
involves: 129 * Black Swiss * C57BL/6 * FVB/N * SJL
abnormal cartilage development J:194283
abnormal cartilage morphology J:194283
abnormal chondrocyte differentiation J:194283
abnormal digit morphology J:194283
abnormal joint morphology J:194283
abnormal limb mesenchyme morphology J:194283
Has2tm1.1Nita/Has2tm1.1Nita
B6.129-Has2tm1.1Nita
no abnormal phenotype detected J:164205
Has2tm1.1Yama/Has2tm1.1Yama
Tg(Prrx1-cre)1Cjt/0
involves: 129X1/SvJ * C57BL/6 * FVB/N * SJL/J
abnormal cartilage morphology J:152912
abnormal chondrocyte morphology J:152912
abnormal digit development J:152912
abnormal gait J:152912
abnormal joint morphology J:152912
abnormal limb development J:152912
abnormal long bone epiphyseal ossification zone morphology J:152912
abnormal long bone epiphyseal plate morphology J:152912
abnormal phalanx morphology J:152912
decreased chondrocyte number J:152912
disorganized long bone epiphyseal plate J:152912
short limbs J:152912
Has2tm1Jam/Has2tm1Jam
involves: 129P2/OlaHsd * C57BL/6J
abnormal blood vessel morphology J:63748
abnormal cardiac epithelial to mesenchymal transition J:63748
abnormal cardiac outflow tract development J:63748
abnormal embryonic tissue morphology J:63748
abnormal extraembryonic endoderm formation J:63748
abnormal head mesenchyme morphology J:63748
abnormal heart morphology J:63748
abnormal somite shape J:63748
abnormal visceral yolk sac morphology J:63748
absent atrioventricular cushions J:63748
absent cardiac jelly J:63748
absent trabeculae carneae J:63748
absent vitelline blood vessels J:63748
decreased heart right ventricle size J:63748
embryonic growth retardation J:63748
embryonic lethality during organogenesis, complete penetrance J:63748
heart atrium hypoplasia J:63748
incomplete embryo turning J:63748
irregular heartbeat J:63748
pericardial edema J:63748

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory