82 phenotypes from 7 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Casp3hith2/Casp3+ involves: A/J * FVB/N	abnormal gait	J:174027
Casp3hith2/Casp3hith2 involves: A/J * FVB/N	cleft palate	J:174027
	encephalomeningocele	J:174027
	prenatal lethality, incomplete penetrance	J:174027
Casp3m1H/Casp3m1H involves: BALB/c * C3H/HeH	decreased apoptosis	J:169366
Casp3mldy/Casp3mldy either: C3H.B6-Casp3mldy or (involves: C3H/HeH * C57BL/6J)	abnormal cochlear hair cell morphology	J:153800
	absent startle reflex	J:153800
	cochlear ganglion degeneration	J:153800
	cochlear hair cell degeneration	J:153800
	cranial bossing	J:153800
	deafness	J:153800
	increased or absent threshold for auditory brainstem response	J:153800
Casp3tm1Dsp/Casp3tm1Dsp involves: 129X1/SvJ	abnormal olfactory bulb development	J:90572
	abnormal olfactory bulb morphology	J:90572
	abnormal olfactory sensory neuron morphology	J:90572
	decreased neuron apoptosis	J:90572
	hydrocephaly	J:90572
	perinatal lethality, incomplete penetrance	J:90572
	premature death	J:90572
Casp3tm1Flv/Casp3+ B6.129S1-Casp3tm1Flv	normal hearing/vestibular/ear phenotype	J:68122
Casp3tm1Flv/Casp3+ involves: 129S1/Sv * C57BL/6J	abnormal bone ossification	J:94703
	abnormal bone remodeling	J:94703
	abnormal sagittal suture morphology	J:94703
	cranioschisis	J:94703
	decreased bone mineral density	J:94703
Casp3tm1Flv/Casp3tm1Flv B6.129S1-Casp3tm1Flv	abnormal apoptosis	J:65496
	abnormal auditory brainstem response waveform shape	J:68122
	abnormal ear morphology	J:68122
	abnormal granulosa cell morphology	J:70205
	abnormal lens development	J:101037
	abnormal lens epithelium morphology	J:101037
	abnormal organ of Corti morphology	J:68122
	abnormal outer hair cell stereociliary bundle morphology	J:68122
	cataract	J:101037
	cochlear degeneration	J:68122
	cochlear ganglion degeneration	J:68122
	cochlear inner hair cell degeneration	J:68122
	cochlear outer hair cell degeneration	J:68122
	deafness	J:68122
	decreased fibroblast apoptosis	J:105496
	decreased sensitivity to induced cell death	J:105496
	fused outer hair cell stereocilia	J:68122
	increased atretic ovarian follicle number	J:70205
	increased or absent threshold for auditory brainstem response	J:68122
	normal reproductive system phenotype	J:70205, J:101037
	normal vision/eye phenotype	J:101037
Casp3tm1Flv/Casp3tm1Flv B6N.129S1-Casp3tm1Flv/J	abnormal keratinocyte physiology	J:189241
	decreased keratinocyte apoptosis	J:189241
	increased cardiomyocyte apoptosis	J:189241
	increased cellular sensitivity to ultraviolet irradiation	J:189241
	increased sensitivity to induced cell death	J:189241
Casp3tm1Flv/Casp3tm1Flv involves: 129S1/Sv * C57BL/6	abnormal blood vessel morphology	J:88367
	abnormal bone marrow development	J:94703
	abnormal bone ossification	J:94703
	abnormal brain morphology	J:36821
	abnormal brainstem morphology	J:36821
	abnormal cerebellar granule layer morphology	J:36821
	abnormal cerebellar molecular layer	J:36821
	abnormal cerebellum development	J:36821
	abnormal cerebellum external granule cell layer morphology	J:36821
	abnormal diencephalon morphology	J:36821
	abnormal eye development	J:88367
	abnormal eye morphology	J:36821
	abnormal forebrain morphology	J:36821
	abnormal optic stalk morphology	J:36821
	abnormal osteoclast physiology	J:94703
	abnormal retina inner nuclear layer morphology	J:88367
	abnormal retina morphology	J:88367
	abnormal retina pigment epithelium morphology	J:88367
	abnormal sagittal suture morphology	J:94703
	abnormal skeleton development	J:94703
	normal cellular phenotype	J:59875, J:66953
	cranioschisis	J:94703
	decreased apoptosis	J:36821
	decreased body size	J:36821
	decreased thymocyte number	J:36821
	decreased trabecular bone thickness	J:94703
	delayed bone ossification	J:94703
	hydrocephaly	J:36821
	normal immune system phenotype	J:36821
	microphthalmia	J:88367
	normal nervous system phenotype	J:88367
	postnatal lethality, complete penetrance	J:36821
	prenatal lethality, incomplete penetrance	J:36821
	normal renal/urinary system phenotype	J:36821
	normal reproductive system phenotype	J:36821
	normal respiratory system phenotype	J:36821
	retina fold	J:88367
	normal vision/eye phenotype	J:88367
Casp3tm1Kin/Casp3tm1Kin B6.129P2-Casp3tm1Kin	absent distortion product otoacoustic emissions	J:69809
	absent pinna reflex	J:69809
	cochlear ganglion degeneration	J:69809
	cochlear inner hair cell degeneration	J:69809
	cochlear outer hair cell degeneration	J:69809
	increased or absent threshold for auditory brainstem response	J:69809
Casp3tm1Mak/Casp3tm1Mak B6.129P2-Casp3tm1Mak	decreased inflammatory response	J:97650, J:179279
	decreased physiological sensitivity to xenobiotic	J:97650
	premature death	J:97650