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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ifngr2
interferon gamma receptor 2
MGI:107654
20 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ifngr2tm1Pbro/Ifngr2tm1Pbro
involves: 129S1/Sv
abnormal class switch recombination J:48016
abnormal T-helper 1 cell differentiation J:48016
decreased susceptibility to type IV hypersensitivity reaction J:48016
increased susceptibility to bacterial infection J:48016
Ifngr2tm1Pbro/Ifngr2tm1Pbro
NOD.129S1-Ifngr2tm1Pbro
abnormal cytotoxic T cell physiology J:72818
abnormal diapedesis J:72818
abnormal T-helper 2 physiology J:65986
decreased susceptibility to autoimmune diabetes J:72818
normal homeostasis/metabolism phenotype J:65986
Tg(CD2-Ifngr2)1Pbro/?
B6.Cg-Tg(CD2-Ifngr2)1Pbro
abnormal T-helper 1 cell differentiation J:134448
abnormal T-helper 1 physiology J:134448
decreased susceptibility to type IV hypersensitivity reaction J:134448
normal immune system phenotype J:134448
increased susceptibility to parasitic infection J:134448
Tg(CD2-Ifngr2)2Pbro/?
B6.Cg-Tg(CD2-Ifngr2)2Pbro
abnormal T-helper 1 cell differentiation J:134448
abnormal T-helper 1 physiology J:134448
normal immune system phenotype J:134448
increased susceptibility to parasitic infection J:134448
Tg(CD2-Ifngr2)2Pbro/?
NOD.Cg-Tg(CD2-Ifngr2)2Pbro
abnormal splenic cell ratio J:81981
abnormal T-helper 1 physiology J:81981
decreased interferon-gamma secretion J:81981
decreased interleukin-4 secretion J:81981
decreased tumor necrosis factor secretion J:81981
normal immune system phenotype J:81981
insulitis J:81981
myositis J:81981
ovary inflammation J:81981
weight loss J:81981

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory