Irgm1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Irgm1
immunity-related GTPase family M member 1
MGI:107567

22 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Irgm1^{em1(IMPC)Wtsi}/Irgm1^{em1(IMPC)Wtsi} C57BL/6N-Irgm1^{em1(IMPC)Wtsi}/Wtsi	abnormal eye morphology	J:211773
	decreased circulating fructosamine level	J:211773
	decreased circulating glucose level	J:211773
	decreased circulating serum albumin level	J:211773
	decreased erythrocyte cell number	J:211773
	decreased fasting circulating glucose level	J:211773
	decreased hematocrit	J:211773
	decreased hemoglobin content	J:211773
	improved glucose tolerance	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating LDL cholesterol level	J:211773
	increased lean body mass	J:211773
	increased mean platelet volume	J:211773
	increased red blood cell distribution width	J:211773
	thrombocytopenia	J:211773
Irgm1^tm1Gat/Irgm1^tm1Gat involves: 129S1/Sv * 129X1/SvJ * C57BL/6	normal immune system phenotype	J:87535
	increased circulating interferon-gamma level	J:87535
	increased circulating interleukin-12 level	J:87535
	increased susceptibility to bacterial infection	J:87535
	increased susceptibility to parasitic infection	J:87535

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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