Sema3c Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
MGI:107557

17 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sema3c^L605P/Sema3c⁺ C57BL/6J-Sema3c^L605P	abnormal heart valve morphology	J:94456
	double outlet right ventricle	J:94456
	interrupted aortic arch	J:94456
	persistent truncus arteriosus	J:94456
Sema3c^L605P/Sema3c^L605P C57BL/6J-Sema3c^L605P	abnormal carotid artery morphology	J:94456
	abnormal extracutaneous pigmentation	J:94456
	double outlet right ventricle	J:94456
	hypopigmentation	J:94456
	interrupted aortic arch	J:94456
	perinatal lethality, incomplete penetrance	J:94456
	persistent truncus arteriosus	J:94456
	semilunar valve regurgitation	J:94456
Sema3c^tm1.1Jra/Sema3c^tm1.1Jra either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6)	perinatal lethality, incomplete penetrance	J:71240
Sema3c^tm1.1Jra/Sema3c^tm1.1Jra involves: 129P2/OlaHsd * CD-1	abnormal common carotid artery morphology	J:71240
	abnormal neural crest cell migration	J:71240
	common truncal valve	J:71240
	double outlet right ventricle	J:71240
	interrupted aortic arch	J:71240
	interrupted aortic arch, type b	J:71240
	interrupted aortic arch, type c	J:71240
	neonatal lethality, incomplete penetrance	J:71240
	normal nervous system phenotype	J:71240
	perimembraneous ventricular septal defect	J:71240
	persistent truncus arteriosus	J:71240

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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