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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Stim1
stromal interaction molecule 1
MGI:107476
84 phenotypes from 9 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Stim1em1(IMPC)Mbp/Stim1+
C57BL/6N-Stim1em1(IMPC)Mbp/MbpMmucd
abnormal eye morphology J:211773
abnormal kidney morphology J:211773
abnormal lymph node morphology J:211773
abnormal placenta morphology J:211773
abnormal placenta vasculature J:211773
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
abnormal vitreous body morphology J:211773
cataract J:211773
decreased exploration in new environment J:211773
embryonic growth retardation J:211773
enlarged heart J:211773
enlarged kidney J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
microphthalmia J:211773
small kidney J:211773
Stim1em1(IMPC)Mbp/Stim1em1(IMPC)Mbp
C57BL/6N-Stim1em1(IMPC)Mbp/MbpMmucd
abnormal placenta morphology J:211773
microphthalmia J:211773
preweaning lethality, complete penetrance J:211773
Stim1Gt(GST050)Byg/Stim1Gt(GST050)Byg
involves: 129P2/OlaHsd
abnormal cell physiology J:178553
Stim1Gt(RRS558)Byg/Stim1Gt(RRS558)Byg
involves: 129P2/OlaHsd
abnormal neuron physiology J:159604
Stim1Gt(RRS558)Byg/Stim1Gt(RRS558)Byg
involves: 129P2/OlaHsd * C57BL/6
abnormal calcium ion homeostasis J:137364
abnormal platelet activation J:137364
abnormal thrombosis J:137364
normal cardiovascular system phenotype J:137364
cyanosis J:137364
decreased platelet aggregation J:137364
normal hematopoietic system phenotype J:137364
normal homeostasis/metabolism phenotype J:137364
neonatal lethality, incomplete penetrance J:137364
postnatal growth retardation J:137364
Stim1Sax/Stim1+
involves: C3HeB/FeJ * C57BL/6
abnormal bone marrow morphology J:127381
abnormal platelet activation J:127381
abnormal thrombopoiesis J:127381
abnormal thrombosis J:127381
enlarged spleen J:127381
normal immune system phenotype J:127381
increased bleeding time J:127381
increased megakaryocyte cell number J:127381
increased spleen red pulp amount J:127381
myelofibrosis J:127381
thrombocytopenia J:127381
Stim1Sax/Stim1Sax
involves: C3HeB/FeJ * C57BL/6
embryonic lethality between somite formation and embryo turning, incomplete penetrance J:127381
hemorrhage J:127381
lethality throughout fetal growth and development, complete penetrance J:127381
Stim1tm1.1Kuro/Stim1+
C57BL/6-Stim1tm1.1Kuro
decreased susceptibility to type I hypersensitivity reaction J:130477
Stim1tm1.1Kuro/Stim1tm1.1Kuro
C57BL/6-Stim1tm1.1Kuro
abnormal cytokine secretion J:130477
abnormal interleukin secretion J:130477
decreased birth body size J:130477
decreased interleukin-6 secretion J:130477
decreased interleukin-13 secretion J:130477
decreased mast cell degranulation J:130477
decreased tumor necrosis factor secretion J:130477
perinatal lethality, complete penetrance J:130477
respiratory failure J:130477
Stim1tm1.1Pg/Stim1+
involves: C57BL/6
abnormal circulating creatine kinase level J:285187
abnormal muscle physiology J:285187
abnormal skeletal muscle fiber morphology J:285187
abnormal skeletal muscle morphology J:285187
abnormal spine curvature J:285187
centrally nucleated skeletal muscle fibers J:285187
decreased body size J:285187
decreased body weight J:285187
decreased gastrocnemius weight J:285187
decreased grip strength J:285187
decreased Ly6C low monocyte number J:285187
decreased NK cell number J:285187
decreased quadriceps weight J:285187
decreased skeletal muscle fiber diameter J:285187
decreased skeletal muscle weight J:285187
enlarged heart J:285187
enlarged spleen J:285187
impaired coordination J:285187
increased bleeding time J:285187
increased Ly6C high monocyte number J:285187
increased soleus weight J:285187
increased variability of skeletal muscle fiber size J:285187
myopathy J:285187
skeletal muscle endomysial fibrosis J:285187
skeletal muscle necrosis J:285187
thrombocytopenia J:285187
tremors J:285187
Stim1tm1.1Rao/Stim1tm1.1Rao
involves: BALB/cJ * C57BL/6 * ICR * SJL
perinatal lethality, incomplete penetrance J:133262
postnatal growth retardation J:133262
postnatal lethality, complete penetrance J:133262
Stim1tm1.1Rao/Stim1tm1.1Rao
involves: BALB/cJ * C57BL/6 * SJL
abnormal cell physiology J:133262
perinatal lethality, incomplete penetrance J:133262
postnatal lethality, complete penetrance J:133262
Stim1tm1Kuro/Stim1tm1Kuro
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * C57BL/6
abnormal B cell physiology J:172608
decreased B cell proliferation J:172608
decreased interleukin-10 secretion J:172608
Stim1tm1Rao/Stim1tm1Rao
Tg(Cd4-cre)1Cwi/0
involves: C57BL/6 * DBA/2 * SJL
abnormal CD4-positive, alpha-beta T cell physiology J:133262
decreased interleukin-2 secretion J:133262
increased lymphocyte cell number J:133262

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory