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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lyst
lysosomal trafficking regulator
MGI:107448
49 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
a/a
Hps6ru-5J/Hps6ru-5J
Lystbg/Lystbg
involves: C3H/Rl * C57BL/6J
abnormal coat/hair pigmentation J:26546
abnormal eye pigmentation J:26546
decreased eye pigmentation J:26546
diluted coat color J:26546
a/a
Hps6ru/Hps6ru
Lystbg/Lystbg
involves: C3H/Rl * C57BL/6J
abnormal melanogenesis J:5346
abnormal melanosome morphology J:5346
abnormal retina melanin granule morphology J:5346
a/a
Lystbg/Lystbg
involves: C3H/Rl * C57BL/6J
abnormal choroid melanin granule morphology J:5346
abnormal retina melanin granule morphology J:5346
a/a
Lystbg/Lystbg
Oca2p-J/Oca2p-J
involves: C3H/HeJ * C3H/Rl * C57BL/6J
abnormal choroid melanin granule morphology J:5346
abnormal melanosome morphology J:5346
a/a
Lystbg/Lystbg
Tyrc/Tyrc
involves: C3H/Rl * C57BL/6J
abnormal choroid melanin granule morphology J:5346
abnormal melanogenesis J:5346
abnormal melanosome morphology J:5346
abnormal retina melanin granule morphology J:5346
a/a
Lystbg/Lystbg
Tyrp1b/Tyrp1b
involves: C3H/Rl * C57BL/6J
abnormal choroid melanin granule morphology J:5346
abnormal retina melanin granule morphology J:5346
A/?
Lystbg/Lystbg
Tyrp1+/?
Not Specified
abnormal eye pigmentation J:29744
decreased ear pigmentation J:29744
decreased tail pigmentation J:29744
diluted coat color J:29744
irregular coat pigmentation J:29744
A/?
Lystbg/Lystbg
Tyrp1b/Tyrp1b
Not Specified
decreased eye pigmentation J:29744
diluted coat color J:29744
Ednrbs/Ednrbs
Lystbg-slt/Lystbg-slt
involves: C57BL/10Ch * Y257/Ch
abnormal eye pigmentation J:25388
Foxq1sa/Foxq1sa
Lystbg/Lystbg
involves: 101/Rl * C3H/Rl * C57BL10/Rl
enlarged spleen J:5311
interstitial pneumonia J:5311
lung inflammation J:5311
weight loss J:5311
Foxq1sa/Foxq1sa
Lystbg/Lystbg
involves: 101/Rl * C3H/Rl * C57BL/6J * C57BL10/Rl
enlarged lymph nodes J:5311
increased lymphoma incidence J:5311
increased susceptibility to infection J:5311
interstitial pneumonia J:5311, J:15166
premature death J:15166
Hps6ru/Hps6ru
Lystbg-slt/Lystbg-slt
involves: YZ57/Ch
decreased eye pigmentation J:25388
diluted coat color J:25388
Lystbg-J/Lystbg-J
Prkdcscid/Prkdcscid
B6.Cg-Lystbg-J Prkdcscid/Sz
abnormal complement pathway J:34814
abnormal granulocyte morphology J:34814
abnormal level of surface class II molecules J:34814
abnormal lymph node morphology J:34814
abnormal neutrophil morphology J:34814
abnormal Peyer's patch morphology J:34814
abnormal spleen white pulp morphology J:34814
abnormal thymus morphology J:34814
decreased B cell number J:34814
decreased CD4-positive, alpha-beta T cell number J:34814
decreased CD8-positive, alpha-beta T cell number J:34814
decreased immunoglobulin level J:34814
decreased lymphocyte cell number J:34814
decreased pre-B cell number J:34814
decreased T cell number J:34814
impaired natural killer cell mediated cytotoxicity J:34814
increased eosinophil cell number J:34814
increased granulocyte number J:34814
increased macrophage cell number J:34814
increased monocyte cell number J:34814
increased neutrophil cell number J:34814
increased NK cell number J:34814
small Peyer's patches J:34814
small thymus J:34814
spleen hypoplasia J:34814
thymus cyst J:34814
Lystbg-slt/Lystbg-slt
Myo5ad/Myo5ad
involves: CT/Ch * YZ57/Ch
diluted coat color J:25388
normal vision/eye phenotype J:25388
Lystbg-slt/Lystbg-slt
Myo5ad/Myo5ad
Oca2p/Oca2p
Tyrp1b/Tyrp1b
involves: CT/Ch * YZ57/Ch
abnormal hair cycle J:83269
delayed hair regrowth J:83269
diluted coat color J:83269
premature hair loss J:83269
Lystbg-slt/Lystbg-slt
Oca2p/Oca2p
involves: CT/Ch * YZ57/Ch
abnormal eye pigmentation J:25388
diluted coat color J:25388
Lystbg/Lystbg
Prkdcscid/Prkdcscid
Not Specified
increased susceptibility to infection J:4752

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory