Capn3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Capn3
calpain 3
MGI:107437

20 phenotypes from 12 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Capn3^{Gt(OST141731)Lex}/Capn3^{Gt(OST141731)Lex} involves: 129S5/SvEvBrd * C57BL/6	abnormal A band morphology	J:91206
	abnormal diaphragm morphology	J:91206
	abnormal gastrocnemius morphology	J:91206
	abnormal muscle morphology	J:91206
	abnormal skeletal muscle fiber morphology	J:91206
	abnormal soleus morphology	J:91206
	abnormal tibialis anterior morphology	J:91206
	decreased body weight	J:91206
	decreased skeletal muscle mass	J:91206
Capn3^tm1.1Hiso/Capn3^tm1.1Hiso B6.129P2-Capn3^tm1.1Hiso	abnormal skeletal muscle fiber morphology	J:163711
	centrally nucleated skeletal muscle fibers	J:163711
	decreased skeletal muscle fiber diameter	J:163711
	dystrophic muscle	J:163711
	increased circulating creatine kinase level	J:163711
	skeletal muscle degeneration	J:163711
Capn3^tm1Jsb/Capn3^tm1Jsb either: 129/Sv-Capn3^tm1Jsb or (involves: 129/Sv * C57BL/6)	abnormal sarcolemma morphology	J:66862
	dystrophic muscle	J:66862
	transmission ratio distortion	J:66862
Tg(ACTA1-Capn3)7.2Spc/0 involves: BALB/c * C57BL/6J	centrally nucleated skeletal muscle fibers	J:77348
Tg(ACTA1-Capn3)7.2Spc/0 involves: BALB/c * C57BL/6J	normal muscle phenotype	J:77348
Tg(ACTA1-Capn3)10.2Spc/0 involves: BALB/c C57BL/6J	no abnormal phenotype detected	J:77348
Tg(ACTA1-Capn3)10.3Spc/0 involves: BALB/c C57BL/6J	centrally nucleated skeletal muscle fibers	J:77348
Tg(ACTA1-Capn3)27.10Spc/0 involves: BALB/c C57BL/6J	abnormal gait	J:77348
	centrally nucleated skeletal muscle fibers	J:77348
	decreased skeletal muscle mass	J:77348
	kyphosis	J:77348
Tg(ACTA1-Capn3)37.3Spc/0 involves: BALB/c C57BL/6J	abnormal gait	J:77348
	centrally nucleated skeletal muscle fibers	J:77348
	decreased skeletal muscle mass	J:77348
	kyphosis	J:77348
Tg(ACTA1-Capn3)37.9Spc/0 involves: BALB/c C57BL/6J	abnormal gait	J:77348
	centrally nucleated skeletal muscle fibers	J:77348
	decreased skeletal muscle mass	J:77348
	kyphosis	J:77348
Tg(ACTA1-Capn3)39.1Spc/0 involves: BALB/c C57BL/6J	abnormal gait	J:77348
	centrally nucleated skeletal muscle fibers	J:77348
	decreased skeletal muscle mass	J:77348
	kyphosis	J:77348
Tg(ACTA1-Capn3)41.1Spc/0 involves: BALB/c C57BL/6J	abnormal gait	J:77348
	centrally nucleated skeletal muscle fibers	J:77348
	decreased skeletal muscle mass	J:77348
	kyphosis	J:77348
Tg(ACTA1-Capn3)42Spc/0 involves: BALB/c C57BL/6J	abnormal gait	J:77348
	centrally nucleated skeletal muscle fibers	J:77348
	decreased skeletal muscle mass	J:77348
	kyphosis	J:77348

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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