Pctp Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pctp
phosphatidylcholine transfer protein
MGI:107375

13 phenotypes from 2 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pctp^R120H/Pctp⁺ NZO	abnormal lipid homeostasis	J:114974
Pctp^tm1Bor/Pctp^tm1Bor B6.129P2-Pctp^tm1Bor	abnormal macrophage physiology	J:115284
Pctp^tm1Bor/Pctp^tm1Bor B6.129P2-Pctp^tm1Bor	increased macrophage apoptosis	J:115284
Pctp^tm1Bor/Pctp^tm1Bor involves: 129P2/OlaHsd * C57BL/6J	abnormal bile canaliculus morphology	J:115285
	abnormal bile composition	J:115285
	abnormal bile salt level	J:115285
	abnormal gallbladder physiology	J:115285
	abnormal phospholipid level	J:115285
	gallstones	J:115285
Pctp^tm1Bor/Pctp^tm1Bor involves: 129P2/OlaHsd * FVB	no abnormal phenotype detected	J:57946
Pctp^tm1Bor/Pctp^tm1Bor involves: 129P2/OlaHsd * FVB/NJ	abnormal bile canaliculus morphology	J:115285
	abnormal bile salt level	J:115285
	abnormal bile secretion	J:115285
	abnormal gallbladder physiology	J:115285
	decreased cholesterol level	J:115285
	increased cholesterol level	J:115285

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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