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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Il17a
interleukin 17A
MGI:107364
27 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Adam17tm1.2Bbl/Adam17tm1.2Bbl
Il17atm1Yiw/Il17atm1Yiw
Sox9tm3(cre)Crm/Sox9+
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * SJL 		dermatitis J:229771
Card14em2Tshu/Card14+
Il17atm1Cdon/Il17atm1Cdon
involves: C57BL/6 		prenatal lethality, complete penetrance J:289239
Card14em3Tshu/Card14+
Il17atm1Cdon/Il17atm1Cdon
involves: C57BL/6 		decreased inflammatory response J:289239
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Il17atm1Yiw/Il17a+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		decreased survivor rate J:191090
glomerulonephritis J:191090
increased plasma cell number J:191090
increased spleen germinal center number J:191090
kidney inflammation J:191090
premature death J:191090
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Il17atm1Yiw/Il17atm1Yiw
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		decreased survivor rate J:191090
decreased susceptibility to systemic lupus erythematosus J:191090
increased anti-double stranded DNA antibody level J:191090
increased anti-nuclear antigen antibody level J:191090
increased double-negative T cell number J:191090
increased plasma cell number J:191090
increased spleen germinal center number J:191090
premature death J:191090
Il1rntm1Yiw/Il1rntm1Yiw
Il17atm1Yiw/Il17a+
involves: 129P2/OlaHsd * BALB/cA * C57BL/6J 		decreased susceptibility to induced arthritis J:83408
Il17atm1Yiw/Il17atm1Yiw
Il1rntm1Yiw/Il1rntm1Yiw
involves: 129P2/OlaHsd * BALB/cA * C57BL/6J 		decreased susceptibility to induced arthritis J:83408
Il17atm1Yiw/Il17atm1Yiw
Il17ftm1Yiw/Il17ftm1Yiw
involves: 129P2/OlaHsd * C57BL/6 		increased susceptibility to bacterial infection J:143719
Il17atm1Yiw/Il17atm1Yiw
Il17ftm1Yiw/Il17ftm1Yiw
Il1rntm1Yiw/Il1rntm1Yiw
involves: 129 * BALB/c 		rheumatoid arthritis J:143719
Il17atm1Yiw/Il17atm1Yiw
Il17ftm2Yiw/Il17ftm2Yiw
B6.129P2-Il17atm1Yiw Il17ftm2Yiw 		decreased IgG3 level J:143719
enlarged submandibular lymph nodes J:143719
increased IgG1 level J:143719
increased IgG2a level J:143719
increased IgG2b level J:143719
increased susceptibility to infection induced morbidity/mortality J:160680
Il17atm1Yiw/Il17atm1Yiw
Il17ftm2Yiw/Il17ftm2Yiw
involves: 129P2/OlaHsd * BALB/c 		decreased IgG3 level J:143719
enlarged submandibular lymph nodes J:143719
increased IgG1 level J:143719
increased IgG2a level J:143719
increased IgG2b level J:143719
increased susceptibility to bacterial infection J:143719
mouth mucosal ulcer J:143719
nasal inflammation J:143719
Il17atm1Yiw/Il17atm1Yiw
Il22tm1Flv/Il22tm1Flv
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 		increased physiological sensitivity to xenobiotic J:126103
Il17atm1Yiw/Il17atm1Yiw
Tg(CD2-Rorc)#Staka/0
involves: 129P2/OlaHsd * C57BL/6 		decreased salivation J:230700
increased susceptibility to autoimmune disorder J:230700
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory