Aff3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Aff3
AF4/FMR2 family, member 3
MGI:106927

24 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Aff3^em1Andg/Aff3⁺ involves: 129S6/SvEvTac * C57BL/6NCrl * CD-1	prenatal lethality	J:317476
Aff3^em1Andg/Aff3^em1Andg chimera involves: 129S6/SvEvTac * C57BL/6NCrl * CD-1	abnormal craniofacial morphology	J:317476
	abnormal fibula morphology	J:317476
	abnormal intestine morphology	J:317476
	abnormal nervous system physiology	J:317476
	abnormal pelvic girdle bone morphology	J:317476
	abnormal tibia morphology	J:317476
	decreased fetal size	J:317476
	decreased length of long bones	J:317476
	delayed bone ossification	J:317476
	polydactyly	J:317476
Aff3^em1Xen/Aff3⁺ involves: C57BL/6N	prenatal lethality	J:317476
Aff3^{tm1a(EUCOMM)Wtsi}/Aff3⁺ C57BL/6N-Aff3^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal vertebral arch morphology	J:211773
Aff3^{tm1a(EUCOMM)Wtsi}/Aff3^{tm1a(EUCOMM)Wtsi} C57BL/6N-Aff3^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal incisor morphology	J:211773
	abnormal snout morphology	J:211773
	abnormal tooth morphology	J:211773
	abnormal vertebral arch morphology	J:211773
	decreased circulating fructosamine level	J:211773
	decreased circulating serum albumin level	J:211773
	decreased corpus callosum size	J:317476
	decreased grip strength	J:211773
	enlarged lateral ventricles	J:317476
	fusion of vertebral arches	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating chloride level	J:211773
	vertebral transformation	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23