Mthfr Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mthfr
methylenetetrahydrofolate reductase
MGI:106639

17 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mthfr^tm1Rzn/Mthfr⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/c	abnormal lipid homeostasis	J:67779
	increased circulating homocysteine level	J:67779
	microvesicular hepatic steatosis	J:67779
Mthfr^tm1Rzn/Mthfr⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl	increased circulating homocysteine level	J:150548
Mthfr^tm1Rzn/Mthfr^tm1Rzn involves: 129S1/Sv * 129X1/SvJ	abnormal blood homeostasis	J:165612
Mthfr^tm1Rzn/Mthfr^tm1Rzn involves: 129S1/Sv * 129X1/SvJ	increased circulating homocysteine level	J:165612
Mthfr^tm1Rzn/Mthfr^tm1Rzn involves: 129S1/Sv * 129X1/SvJ * BALB/c	abnormal cerebellar granule layer morphology	J:67779
	abnormal lipid homeostasis	J:67779
	decreased body weight	J:67779
	delaminated Purkinje cell layer	J:67779
	delayed sexual maturation	J:67779
	exophthalmos	J:67779
	increased circulating homocysteine level	J:67779
	kinked tail	J:67779
	kyphosis	J:67779
	microvesicular hepatic steatosis	J:67779
	postnatal growth retardation	J:67779
	premature death	J:67779
	short tail	J:67779
	small cerebellum	J:67779
	sparse hair	J:67779
Mthfr^tm1Rzn/Mthfr^tm1Rzn involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl	normal homeostasis/metabolism phenotype	J:150548
	increased circulating homocysteine level	J:150548

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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