About   Help   FAQ
Due to maintenance, access to MGI may be intermittent 8:00 AM ET Wed, September 18.
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Nrp1
neuropilin 1
MGI:106206
59 phenotypes from 7 alleles in 12 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Nrp1tm1.1Cruh/Nrp1tm1.1Cruh
involves: C57BL/6
abnormal retinal blood vessel pattern J:176047
normal cardiovascular system phenotype J:176047
Nrp1tm1.1Izac/Nrp1tm1.1Izac
involves: 129S2/SvPas * C57BL/6
abnormal brain vasculature morphology J:208348
abnormal coronary artery morphology J:208348
abnormal coronary vessel morphology J:208348
abnormal induced retinal neovascularization J:208348
abnormal retinal blood vessel morphology J:208348
abnormal retinal vasculature morphology J:208348
decreased angiogenesis J:208348
decreased body size J:208348
decreased tumor growth/size J:208348
postnatal lethality, incomplete penetrance J:208348
premature death J:208348
vascular smooth muscle hypoplasia J:208348
Nrp1tm1b(EUCOMM)Hmgu/Nrp1tm1b(EUCOMM)Hmgu
C57BL/6N-Nrp1tm1b(EUCOMM)Hmgu/Orl
preweaning lethality, complete penetrance J:211773
Nrp1tm1Ddg/Nrp1tm1Ddg
involves: 129P2/OlaHsd
abnormal dendritic cell physiology J:161856
abnormal T cell physiology J:161856
normal vision/eye phenotype J:172268
Nrp1tm1Ddg/Nrp1tm1Ddg
involves: 129P2/OlaHsd * C57BL/6
abnormal axon guidance J:93799
abnormal corpus callosum morphology J:93799
abnormal cranial nerve morphology J:93799
abnormal dorsal root ganglion morphology J:93799
abnormal hippocampus morphology J:93799
abnormal spinal nerve morphology J:93799
abnormal trigeminal nerve morphology J:93799
abnormal vestibulocochlear nerve morphology J:93799
dilated heart atrium J:93799
postnatal growth retardation J:93799
postnatal lethality J:93799
Nrp1tm1Ddg/Nrp1tm1Ddg
Tg(Thy1-YFP)16Jrs/0
involves: 129P2/OlaHsd * C57BL/6
abnormal cerebral cortex pyramidal cell morphology J:93799
Nrp1tm1Hfu/Nrp1tm1Hfu
involves: C57BL/6 * CBA
abnormal axon guidance J:98330
abnormal spinal nerve morphology J:98330
abnormal trigeminal nerve morphology J:98330
abnormal vascular development J:75477
embryonic lethality during organogenesis, complete penetrance J:75477
transposition of great arteries J:75477
Nrp1tm1Hfu/Nrp1tm1Hfu
involves: C57BL/6 * CBA * ICR
abnormal aortic arch and aortic arch branch attachment J:58077
abnormal dorsal aorta morphology J:58077
abnormal first pharyngeal arch artery morphology J:58077
abnormal fourth pharyngeal arch artery morphology J:58077
abnormal pharyngeal arch artery morphology J:58077
abnormal pulmonary artery morphology J:58077
abnormal second pharyngeal arch artery morphology J:58077
abnormal sixth pharyngeal arch artery morphology J:58077
abnormal third pharyngeal arch artery morphology J:58077
decreased angiogenesis J:58077
disorganized yolk sac vascular plexus J:58077
double aortic arch J:58077
embryonic lethality, complete penetrance J:58077
persistent truncus arteriosis J:58077
right aortic arch J:58077
Nrp1tm1Hfu/Nrp1tm1Hfu
involves: C57BL/6NCrlj * CBA/JNCrlj
normal nervous system phenotype J:175836
Nrp1tm1Hfu/Nrp1tm1Hfu
involves: CD-1 * JF1
abnormal facial motor nucleus morphology J:94050
abnormal facial nerve morphology J:94050
abnormal neuronal migration J:94050
abnormal trigeminal nerve morphology J:94050
Nrp1tm1Hfu/Nrp1tm2Ddg
Tg(Tek-cre)1Ywa/0
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * SJL
abnormal brain vasculature morphology J:175836
decreased neuron number J:175836
Nrp1tm2.1Ddg/Nrp1tm2.1Ddg
involves: 129 * C57BL/6
abnormal spinal nerve morphology J:93799
abnormal trigeminal nerve morphology J:93799
Nrp1tm2Ddg/Nrp1tm2.1Ddg
Tg(Gucy2g-cre,-EGFP)52Irod/0
involves: 129P2/OlaHsd * C57BL/6 * SJL
abnormal accessory olfactory bulb morphology J:185650
normal nervous system phenotype J:185650
Nrp1tm2Ddg/Nrp1tm2.1Ddg
Tg(Tek-cre)1Ywa/0
involves: 129 * C57BL/6
abnormal blood vessel morphology J:93799
dilated heart atrium J:93799
failure of vascular branching J:93799
persistent truncus arteriosis J:93799
prenatal lethality, complete penetrance J:93799
Nrp1tm2Ddg/Nrp1tm2Ddg
Tg(Tek-cre)1Ywa/0
involves: 129 * C57BL/6
abnormal cardiovascular system morphology J:93799
abnormal coronary vessel morphology J:93799
perinatal lethality, complete penetrance J:93799
persistent truncus arteriosis J:93799
ventricular septal defect J:93799

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/10/2019
MGI 6.14
The Jackson Laboratory