Ccr2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccr2
C-C motif chemokine receptor 2
MGI:106185

33 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
A^y/a Apoe^tm1Unc/Apoe^tm1Unc Ccr2^tm1Mae/Ccr2^tm1Mae involves: 129P2/OlaHsd * C57BL/6J * KK/TaJcl	decreased circulating adiponectin level	J:177084
	normal homeostasis/metabolism phenotype	J:177084
	increased circulating cholesterol level	J:177084
	increased circulating leptin level	J:177084
Apoe^tm1Unc/Apoe^tm1Unc Ccr2^tm1Ifc/Ccr2⁺ involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6	decreased susceptibility to atherosclerosis	J:111471
Apoe^tm1Unc/Apoe^tm1Unc Ccr2^tm1Ifc/Ccr2^tm1Ifc B6.Cg-Apoe^tm1Unc Ccr2^tm1Ifc	decreased monocyte cell number	J:153310
	decreased susceptibility to atherosclerosis	J:153310
Apoe^tm1Unc/Apoe^tm1Unc Ccr2^tm1Ifc/Ccr2^tm1Ifc involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6	decreased susceptibility to atherosclerosis	J:111471
	impaired macrophage chemotaxis	J:111471
Apoe^tm1Unc/Apoe^tm1Unc Ccr2^tm1Ifc/Ccr2^tm1Ifc Cx3cl1^tm1Lira/Cx3cl1^tm1Lira B6.Cg-Apoe^tm1Unc Cx3cl1^tm1Lira Ccr2^tm1Ifc	decreased monocyte cell number	J:153310
	decreased susceptibility to atherosclerosis	J:153310
Ccl2^tm1Rol/Ccl2^tm1Rol Ccr2^tm1Mae/Ccr2^tm1Mae B6.129-Ccr2^tm1Mae Ccl2^tm1Rol	alcohol aversion	J:102583
	alcohol preference	J:102583
	decreased alcohol consumption	J:102583
Ccr2^{tm1.1(CCR2)Rodb}/Ccr2^{tm1.1(CCR2)Rodb} Lepr^db/Lepr^db involves: C57BL/6 * C57BLKS/J	abnormal urine protein level	J:203000
Ccr2^tm1Blck/Ccr2^tm1Blck Fas^lpr/Fas^lpr MRL.Cg-Ccr2^tm1Blck Fas^lpr	abnormal immune system organ morphology	J:113343
	abnormal interferon level	J:113343
	abnormal lymphocyte cell number	J:113343
	abnormal renal glomerulus morphology	J:113343
	abnormal tumor necrosis factor level	J:113343
	albuminuria	J:113343
	enlarged lymph nodes	J:113343
	enlarged spleen	J:113343
	expanded mesangial matrix	J:113343
	glomerulonephritis	J:113343
	glomerulosclerosis	J:113343
	kidney inflammation	J:113343
	premature death	J:113343
	renal tubule atrophy	J:113343
Ccr2^tm1Ifc/Ccr2⁺ Tg(APPSWE)2576Kha/0 involves: 129S4/SvJae * C57BL/6 * SJL	premature death	J:121703
Ccr2^tm1Ifc/Ccr2^tm1Ifc Tg(APPSWE)2576Kha/0 involves: 129S4/SvJae * C57BL/6 * SJL	abnormal microglial cell physiology	J:121703
	amyloid beta deposits	J:121703
	amyloidosis	J:121703
	intracranial hemorrhage	J:121703
	premature death	J:121703
Ccr2^tm1Mae/Ccr2^tm1Mae Msmp^em1Jzx/Msmp^em1Jzx involves: 129P2/OlaHsd * C57BL/6	decreased circulating alanine transaminase level	J:311042
	decreased susceptibility to injury	J:311042
Ccr2^tm2.1Ifc/Ccr2^tm2.1Ifc Cx3cr1^tm1Litt/Cx3cr1⁺ involves: 129P2/OlaHsd * C57BL/6 * FVB/N	abnormal leukocyte physiology	J:166664
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:166664
Ccr2^tm2.1Ifc/Ccr2^tm2.1Ifc Cx3cr1^tm1Litt/Cx3cr1^tm1Litt involves: 129P2/OlaHsd * C57BL/6 * FVB/N	abnormal leukocyte physiology	J:166664
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:166664

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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