Tfap2c Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tfap2c
transcription factor AP-2, gamma
MGI:106032

29 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tfap2c^tm1.1Hsc/Tfap2c⁺ involves: 129P2/OlaHsd	decreased body size	J:78934
Tfap2c^tm1.1Hsc/Tfap2c^tm1.1Hsc involves: 129P2/OlaHsd	abnormal trophoblast giant cell morphology	J:78934
	absent mesoderm	J:78934
	absent placental labyrinth	J:78934
	decreased embryo size	J:78934
	decreased trophoblast giant cell number	J:78934
	embryonic lethality during organogenesis, complete penetrance	J:78934
	small ectoplacental cone	J:78934
Tfap2c^tm1Hsc/Tfap2c^tm1Hsc involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:75122
Tfap2c^tm1Will/Tfap2c^tm1Will involves: 129S1/Sv * Black Swiss	abnormal developmental patterning	J:76369
	abnormal dorsal-ventral axis patterning	J:76369
	abnormal embryonic tissue morphology	J:76369
	abnormal embryonic-extraembryonic boundary morphology	J:76369
	abnormal extraembryonic coelom morphology	J:76369
	abnormal extraembryonic ectoderm morphology	J:76369
	abnormal extraembryonic tissue morphology	J:76369
	abnormal mesoderm development	J:76369
	abnormal Reichert's membrane morphology	J:76369
	absent allantois	J:76369
	absent ectoplacental cavity	J:76369
	absent ectoplacental cone	J:76369
	absent mesoderm	J:76369
	decreased trophoblast giant cell number	J:76369
	disorganized embryonic tissue	J:76369
	disorganized extraembryonic tissue	J:76369
	embryonic growth retardation	J:76369
	embryonic lethality between implantation and somite formation, incomplete penetrance	J:76369
	embryonic lethality during organogenesis, complete penetrance	J:76369
	failure of primitive streak formation	J:76369
	failure to gastrulate	J:76369
	small ectoplacental cone	J:76369
	small embryonic epiblast	J:76369
Tfap2c^tm1Will/Tfap2c^tm2Will Tg(Zp3-cre)3Mrt/0 involves: 129S1/Sv * FVB/N	normal embryo phenotype	J:113442

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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