Dmc1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dmc1
DNA meiotic recombinase 1
MGI:105393

25 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dmc1^em1Jcs/Dmc1^em1Jcs involves: C57BL/6J * FVB/NJ	normal reproductive system phenotype	J:267449
Dmc1^em1Jcs/Dmc1^tm1Jcs involves: 129S4/SvJae * C57BL/6J * FVB/NJ	normal reproductive system phenotype	J:267449
Dmc1^Mei11/Dmc1⁺ involves: 129S4/SvJae * C3HeB/FeJ * C57BL/6J	abnormal female meiosis	J:122037
	abnormal ovarian follicle morphology	J:122037
	abnormal spermatocyte morphology	J:122037
	arrest of male meiosis	J:122037
	decreased oocyte number	J:122037
	male infertility	J:122037
	reduced female fertility	J:122037
Dmc1^Mei11/Dmc1⁺ involves: 129S4/SvJae * C57BL/6J	abnormal female meiosis	J:122037
	abnormal ovarian follicle morphology	J:122037
	arrest of male meiosis	J:122037
	male infertility	J:122037
Dmc1^Mei11/Dmc1^Mei11 involves: 129S4/SvJae * C57BL/6J	abnormal seminiferous tubule morphology	J:60747
	abnormal spermiogenesis	J:60747
	decreased male germ cell number	J:60747
	male infertility	J:60747
Dmc1^tm1Jcs/Dmc1^Mei11 involves: 129S4/SvJae * C57BL/6J	abnormal ovarian follicle morphology	J:122037
	abnormal spermatocyte morphology	J:122037
	absent ovarian follicles	J:122037
	arrest of male meiosis	J:122037
	decreased oocyte number	J:122037
	female infertility	J:122037
Dmc1^tm1Jcs/Dmc1^tm1Jcs involves: 129S4/SvJae * C57BL/6	abnormal male meiosis	J:194067
Dmc1^tm1Jcs/Dmc1^tm1Jcs involves: 129S4/SvJae * C57BL/6J	abnormal female meiosis	J:47308
	abnormal gametogenesis	J:47308
	abnormal oogenesis	J:47308
	abnormal reproductive system morphology	J:47308
	abnormal spermatogenesis	J:47308
	absent oocytes	J:47308, J:183982
	absent ovarian follicles	J:47308
	arrest of male meiosis	J:47308
	azoospermia	J:47308
	decreased ovary weight	J:47308
	decreased testis weight	J:47308
	female infertility	J:47308
	infertility	J:47308
	male infertility	J:47308
Dmc1^tm1Tkm/Dmc1^tm1Tkm involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal gametogenesis	J:47307
	abnormal oogenesis	J:47307
	abnormal spermatogenesis	J:47307
	absent oocytes	J:47307
	absent ovarian follicles	J:47307
	arrest of male meiosis	J:47307
	azoospermia	J:47307
	infertility	J:47307
	male infertility	J:47307
	small ovary	J:47307
	small testis	J:47307

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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