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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cdkn2c
cyclin dependent kinase inhibitor 2C
MGI:105388
50 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Cdkn2ctm1Bbd/Cdkn2ctm1Bbd
involves: 129S1/Sv * C57BL/6
abnormal apoptosis J:68829
abnormal cerebellar molecular layer J:102702
abnormal Leydig cell differentiation J:68829
abnormal lymph node medulla morphology J:63299
abnormal mammary gland epithelium morphology J:63299
abnormal neuron differentiation J:102702
abnormal neuronal migration J:102702
cortical renal glomerulopathies J:63299
decreased circulating testosterone level J:68829
decreased tumor-free survival time J:63299
enlarged lymph nodes J:63299
enlarged spleen J:63299
enlarged testis J:68829
increased B cell derived lymphoma incidence J:63299
increased body size J:63299
increased body weight J:63299
increased hemangiosarcoma incidence J:63299
increased Leydig cell number J:68829
increased pheochromocytoma incidence J:63299
increased pituitary adenoma incidence J:63299
increased renal carcinoma incidence J:63299
increased spleen white pulp amount J:63299
increased T cell derived lymphoma incidence J:63299
increased testis tumor incidence J:63299
kidney cortex cyst J:63299
kidney cyst J:63299
lymphoid hyperplasia J:63299
mammary gland hyperplasia J:63299
normal neoplasm J:102702
pituitary gland hyperplasia J:63299
Cdkn2ctm1Yxi/Cdkn2ctm1Yxi
B6.129-Cdkn2ctm1Yxi
increased bronchioalveolar stem cell number J:120835
increased lung adenocarcinoma incidence J:120835
increased lung adenoma incidence J:120835
increased lung tumor incidence J:120835
Cdkn2ctm1Yxi/Cdkn2ctm1Yxi
C.129-Cdkn2ctm1Yxi
abnormal mammary gland morphology J:198018
increased mammary gland tumor incidence J:198018
Cdkn2ctm1Yxi/Cdkn2ctm1Yxi
involves: 129/Sv * C57BL/6 * DBA/2
abnormal pituitary intermediate lobe morphology J:50053
abnormal T cell physiology J:50053
abnormal thymus size J:50053
ataxia J:50053
dehydration J:50053
enlarged adrenal glands J:50053
enlarged pituitary gland J:50053
enlarged spleen J:50053
increased B cell number J:50053
increased body size J:50053
increased body weight J:50053
increased bone marrow cell number J:50053
increased pituitary adenoma incidence J:50053
increased T cell number J:50053
pituitary gland hyperplasia J:50053
small testis J:50053
spleen hyperplasia J:50053
thymus hyperplasia J:50053
weight loss J:50053

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory