93 phenotypes from 4 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cxcr2tm1(IL8RB)Dktr/Cxcr2tm1(IL8RB)Dktr involves: 129S2/SvPas * C57BL/6	decreased kidney weight	J:113489
	decreased spleen weight	J:113489
	normal immune system phenotype	J:113489
	increased granulocyte number	J:113489
	increased leukocyte cell number	J:113489
	small adrenal glands	J:113489
	small liver	J:113489
Cxcr2tm1a(EUCOMM)Wtsi/Cxcr2+ C57BL/6N-Cxcr2tm1a(EUCOMM)Wtsi/Wtsi	increased circulating creatinine level	J:211773
	increased circulating magnesium level	J:211773
Cxcr2tm1a(EUCOMM)Wtsi/Cxcr2tm1a(EUCOMM)Wtsi C57BL/6N-Cxcr2tm1a(EUCOMM)Wtsi/Wtsi	decreased B cell number	J:211773
	decreased CD8-positive, alpha-beta T cell number	J:211773
	decreased circulating fructosamine level	J:211773
	decreased circulating serum albumin level	J:211773
	decreased circulating thyroxine level	J:211773
	decreased immature B cell number	J:211773
	decreased mature B cell number	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased pre-B cell number	J:211773
	decreased pre-pro B cell number	J:211773
	decreased T cell number	J:211773
	improved glucose tolerance	J:211773
	increased anti-nuclear antigen antibody level	J:211773
	increased CD4-positive, alpha-beta memory T cell number	J:211773
	increased CD8-positive, alpha-beta memory T cell number	J:211773
	increased CD103-positive CD11b-low dendritic cell number	J:211773
	increased circulating calcium level	J:211773
	increased circulating total protein level	J:211773
	increased effector memory CD8-positive, alpha-beta T cell number	J:211773
	increased effector memory T-helper cell number	J:211773
	increased eosinophil cell number	J:211773
	increased gamma-delta T cell number	J:211773
	increased granulocyte number	J:211773
	increased KLRG1+ CD4 alpha-beta T cell number	J:211773
	increased KLRG1+ CD8 alpha-beta T cell number	J:211773
	increased leukocyte cell number	J:211773
	increased Ly6C high monocyte number	J:211773
	increased Ly6C low monocyte number	J:211773
	increased memory-marker CD4-positive NK T cell number	J:211773
	increased memory-marker gamma-delta T cell number	J:211773
	increased memory-marker NK cell number	J:211773
	increased monocyte cell number	J:211773
	increased neutrophil cell number	J:211773
	increased red blood cell distribution width	J:211773
	thrombocytosis	J:211773
Cxcr2tm1Mwm/Cxcr2+ C.129S2(B6)-Cxcr2tm1Mwm/J	delayed wound healing	J:63935
	impaired neutrophil recruitment	J:63935
Cxcr2tm1Mwm/Cxcr2tm1Mwm B6.Cg-Il8rbtm1Mwm	abnormal tumor morphology	J:88233
	decreased metastatic potential	J:88233
	decreased tumor growth/size	J:88233
Cxcr2tm1Mwm/Cxcr2tm1Mwm C.129S2(B6)-Cxcr2tm1Mwm/J	abnormal airway responsiveness	J:73947
	abnormal chemokine level	J:73947
	abnormal cytokine secretion	J:72824
	abnormal eosinophil physiology	J:73947
	abnormal interleukin level	J:73947, J:87365
	abnormal leukocyte physiology	J:94170
	abnormal myelination	J:78470
	abnormal neutrophil physiology	J:73947, J:93946
	abnormal NK T cell physiology	J:66399
	abnormal respiratory mucosa goblet cell morphology	J:82293
	abnormal spinal cord morphology	J:78470
	abnormal T cell physiology	J:73947
	abnormal T-helper 1 physiology	J:73947
	abnormal T-helper 2 physiology	J:73947
	corneal vascularization	J:87365
	decreased airway responsiveness	J:82293
	decreased oligodendrocyte progenitor number	J:78470
	decreased susceptibility to fungal infection	J:73947
	decreased susceptibility to induced arthritis	J:142880
	decreased susceptibility to induced morbidity/mortality	J:85647
	delayed wound healing	J:63935
	impaired neutrophil chemotaxis	J:65905, J:72824
	impaired neutrophil recruitment	J:63935, J:65425, J:93116
	increased IgE level	J:73947
	increased susceptibility to bacterial infection	J:65905
	increased susceptibility to Herpesvirales infection	J:87365
	increased susceptibility to parasitic infection	J:72824
Cxcr2tm1Mwm/Cxcr2tm1Mwm involves: 129S2/SvPas	decreased susceptibility to bacterial infection induced morbidity/mortality	J:208901
Cxcr2tm1Mwm/Cxcr2tm1Mwm involves: 129S2/SvPas * BALB/c	abnormal myelopoiesis	J:113489
	abnormal neutrophil physiology	J:113489
	decreased body size	J:113489
	decreased thymus weight	J:113489
	extramedullary hematopoiesis	J:113489
	increased epididymis weight	J:113489
	increased granulocyte number	J:113489
	increased kidney weight	J:113489
	increased seminal vesicle weight	J:113489
	increased spleen weight	J:113489
Cxcr2tm1Mwm/Cxcr2tm1Mwm involves: 129S2/SvPas * C57BL/6J	abnormal bone marrow morphology	J:19570
	abnormal granulocyte differentiation	J:19570
	abnormal myelopoiesis	J:19570
	abnormal spleen white pulp morphology	J:19570
	enlarged cervical lymph nodes	J:19570
	enlarged lymph nodes	J:19570
	enlarged spleen	J:19570
	normal hematopoietic system phenotype	J:19570
	impaired neutrophil chemotaxis	J:19570
	increased B cell number	J:19570
	increased circulating interleukin-6 level	J:19570
	increased neutrophil cell number	J:19570
	lymph node medullary cord hyperplasia	J:19570
	myeloid hyperplasia	J:19570
Cxcr2tm1Rmra/Cxcr2tm1Rmra Tg(Mx1-cre)1Cgn/0 involves: 129S/SvEv * C57BL/6 * C57BL/6NTac * CBA	abnormal neutrophil physiology	J:204482
	weight loss	J:204482