98 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Krastm4Tyj/Kras+ Rbl2tm2Tyj/Rbl2tm2Tyj involves: 129S4/SvJae	abnormal bronchiole morphology	J:147590
	abnormal tumor morphology	J:147590
	increased lung adenocarcinoma incidence	J:147590
	increased lung tumor incidence	J:147590
	increased tumor growth/size	J:147590
	premature death	J:147590
	thick pulmonary interalveolar septum	J:147590
Rb1tm2Brn/Rb1tm2Brn Rbl1tm1Tyj/Rbl1tm1Tyj Rbl2tm2Tyj/Rbl2tm2Tyj involves: 129 * 129S2/SvPas * 129S4/SvJae	hematuria	J:217195
	increased urinary bladder carcinoma incidence	J:217195
Rb1tm2Brn/Rb1tm2Brn Rbl2tm1Tyj/Rbl2tm1Tyj Tg(Myh6-cre)2182Mds/Tg(Myh6-cre)2182Mds involves: 129 * 129S2/SvPas * FVB/N	abnormal myocardial fiber physiology	J:97589
	decreased heart rate	J:97589
	decreased ventricle muscle contractility	J:97589
	dilated heart left ventricle	J:97589
	edema	J:97589
	enlarged heart	J:97589
	increased myocardial fiber size	J:97589
	premature death	J:97589
	respiratory distress	J:97589
Rb1tm3Tyj/Rb1tm3Tyj Rbl1tm1Tyj/Rbl1tm1Tyj Rbl2tm2.1Tyj/Rbl2tm2.1Tyj involves: 129S2/SvPas * 129S4/SvJae * C57BL/6	increased hepatocellular carcinoma incidence	J:177573
Rb1tm3Tyj/Rb1tm3Tyj Rbl2tm1Tyj/Rbl2tm1Tyj Tg(Nes-cre)1Atp/0 involves: 129S2/SvPas * 129S4/SvJae * FVB/N	abnormal retina apoptosis	J:91406
	decreased tumor-free survival time	J:91406
	increased retinoblastoma incidence	J:91406
	transmission ratio distortion	J:91406
Rb1tm3Tyj/Rb1tm3Tyj Rbl2tm2.1Tyj/Rbl2tm2.1Tyj Tg(Pax6-cre,GFP)2Pgr/0 involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 * FVB/N	abnormal amacrine cell morphology	J:119919
	abnormal retina horizontal cell morphology	J:119919
	abnormal retina morphology	J:119919
	abnormal retina neuronal layer morphology	J:119919
	absent retina bipolar cells	J:119919
	absent retina ganglion cell	J:119919
	decreased retina cone cell number	J:119919
	increased retina apoptosis	J:119919
	increased retinoblastoma incidence	J:119919
	premature death	J:119919
	retina hypoplasia	J:119919
Rb1tm3Tyj/Rb1tm3Tyj Rbl2tm2Tyj/Rbl2tm2Tyj Trp53tm1Brn/Trp53tm1Brn involves: 129P2/OlaHsd * 129S4/SvJae	increased lung small cell carcinoma incidence	J:160148
	increased lung tumor incidence	J:160148
	premature death	J:160148
Rbl1tm1.1Fad/Rbl1tm1.1Fad Rbl2tm1Tyj/Rbl2tm1Tyj involves: 129S2/SvPas * C57BL/6 * FVB/N	abnormal bone mineralization	J:217445
	abnormal long bone epiphyseal ossification zone morphology	J:217445
	abnormal long bone epiphyseal plate proliferative zone	J:217445
	abnormal middle ear ossicle morphology	J:217445
	abnormal scapular spine morphology	J:217445
	normal cellular phenotype	J:217445
	decreased body size	J:217445
	decreased length of long bones	J:217445
	decreased long bone epiphyseal plate size	J:217445
	interparietal bone hypoplasia	J:217445
	neonatal lethality, incomplete penetrance	J:217445
	postnatal lethality, complete penetrance	J:217445
	short femur	J:217445
	short fibula	J:217445
	short radius	J:217445
	short tibia	J:217445
	short ulna	J:217445
	small supraoccipital bone	J:217445
Rbl1tm1Tyj/Rbl1+ Rbl2tm1Tyj/Rbl2tm1Tyj involves: 129S2/SvPas * C57BL/6	normal limbs/digits/tail phenotype	J:34725
	postnatal growth retardation	J:34725
Rbl1tm1Tyj/Rbl1tm1Tyj Rbl2tm1Tyj/Rbl2+ involves: 129S2/SvPas * C57BL/6	abnormal forelimb morphology	J:34725
	decreased body weight	J:34725
	delayed fertility	J:34725
	distended abdomen	J:34725
	postnatal lethality, incomplete penetrance	J:34725
	reduced female fertility	J:34725
	short forelimb	J:34725
	short limbs	J:34725
	short snout	J:34725
Rbl1tm1Tyj/Rbl1tm1Tyj Rbl2tm1Tyj/Rbl2tm1Tyj involves: 129S2/SvPas * C57BL/6	abnormal awl hair morphology	J:82802
	abnormal breathing pattern	J:34725
	abnormal chondrocyte morphology	J:34725
	abnormal craniofacial bone morphology	J:34725
	abnormal epidermis stratum granulosum morphology	J:82802
	abnormal forelimb morphology	J:34725
	abnormal guard hair morphology	J:82802
	abnormal hair cycle	J:82802
	abnormal hair follicle development	J:82802
	abnormal hair follicle orientation	J:82802
	abnormal humerus morphology	J:34725
	abnormal keratinocyte differentiation	J:82802
	abnormal limb bone morphology	J:34725
	abnormal long bone epiphyseal plate morphology	J:34725
	abnormal long bone epiphyseal plate proliferative zone	J:34725
	abnormal rib development	J:34725
	abnormal supraoccipital bone morphology	J:34725
	abnormal tooth development	J:82802
	abnormal tracheal cartilage morphology	J:34725
	abnormal zigzag hair morphology	J:82802
	absent incisors	J:82802
	apnea	J:34725
	decreased body size	J:34725
	decreased fetal size	J:34725
	decreased hair follicle number	J:82802
	delayed emergence of vibrissae	J:82802
	delayed endochondral bone ossification	J:34725
	distended abdomen	J:34725
	enlarged sebaceous gland	J:82802
	epidermal hyperplasia	J:82802
	increased diameter of humerus	J:34725
	increased diameter of radius	J:34725
	increased diameter of ulna	J:34725
	increased width of hypertrophic chondrocyte zone	J:34725
	interparietal bone hypoplasia	J:34725
	neonatal lethality, complete penetrance	J:34725
	parakeratosis	J:82802
	perinatal lethality, incomplete penetrance	J:34725
	short humerus	J:34725
	short limbs	J:34725
	short radius	J:34725
	short snout	J:34725
	short ulna	J:34725
	small incisors	J:82802
	small thoracic cage	J:34725
	underdeveloped hair follicles	J:82802