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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Rab10
RAB10, member RAS oncogene family
MGI:105066
26 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Rab10em1(IMPC)J/Rab10+
C57BL/6NJ-Rab10em1(IMPC)J/Mmjax
abnormal auditory brainstem response J:211773
decreased mean corpuscular hemoglobin J:211773
decreased mean corpuscular volume J:211773
increased startle reflex J:211773
iris synechia J:211773
Rab10em1(IMPC)J/Rab10em1(IMPC)J
C57BL/6NJ-Rab10em1(IMPC)J/Mmjax
embryonic lethality prior to organogenesis J:211773
preweaning lethality, complete penetrance J:211773
Rab10tm1c(KOMP)Wtsi/Rab10tm1c(KOMP)Wtsi
Tg(Adipoq-cre)1Evdr/0
involves: C57BL/6J * C57BL/6N * FVB/NJ
normal adipose tissue phenotype J:249843
decreased adipocyte glucose uptake J:249843
normal homeostasis/metabolism phenotype J:249843
increased circulating insulin level J:249843
increased hepatic glucose production J:249843
insulin resistance J:249843
Rab10tm1Tax/Rab10tm1Tax
B6.Cg-Rab10tm1Tax
abnormal cell nucleus morphology J:262459
abnormal extraembryonic ectoderm morphology J:262459
abnormal extraembryonic tissue morphology J:262459
abnormal germ layer development J:262459
abnormal vacuole morphology J:262459
absent amniotic cavity J:262459
absent ectoplacental cavity J:262459
absent extraembryonic coelom J:262459
decreased cell proliferation J:262459
decreased embryo size J:262459
embryonic growth arrest J:262459
embryonic lethality between somite formation and embryo turning, complete penetrance J:262459
failure of primitive streak formation J:262459

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory