Pls1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pls1
plastin 1 (I-isoform)
MGI:104809

20 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Pls1^tm1Fri/Pls1^tm1Fri B6.129-Pls1^tm1Fri	abnormal hair cell mechanoelectric transduction	J:216416
	abnormal inner hair cell stereociliary bundle morphology	J:216416
	abnormal intestinal epithelium morphology	J:216723
	abnormal intestine physiology	J:216723
	abnormal outer hair cell stereociliary bundle morphology	J:216416
	normal behavior/neurological phenotype	J:216723
	decreased inner hair cell stereocilia number	J:216416
	decreased small intestinal microvillus size	J:216723
	fused outer hair cell stereocilia	J:216416
	normal growth/size/body region phenotype	J:216723
	normal homeostasis/metabolism phenotype	J:216723
	impaired hearing	J:216416
	increased enterocyte apoptosis	J:216723
	increased or absent threshold for auditory brainstem response	J:216416
	increased susceptibility to colitis induced morbidity/mortality	J:216723
	increased susceptibility to induced colitis	J:216723
	normal mortality/aging	J:216723
	normal reproductive system phenotype	J:216723
	short inner hair cell stereocilia	J:216416
	thin cochlear hair cell stereocilia	J:216416

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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