81 phenotypes from 4 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kcnj6em1(IMPC)H/Kcnj6em1(IMPC)H C57BL/6N-Kcnj6em1(IMPC)H/H	decreased anxiety-related response	J:211773
	hyperactivity	J:211773
	impaired righting response	J:211773
	increased circulating amylase level	J:211773
	increased exploration in new environment	J:211773
Kcnj6em1.1Ktaka/Kcnj6em1.1Ktaka Slc6a3tm1.1(cre)Bkmn/Slc6a3+ involves: C57BL/6J * C57BL/6N	abnormal nervous system electrophysiology	J:257982
	behavioral despair	J:257982
Kcnj6tm1Stf/Kcnj6tm1Stf involves: 129S1/Sv * 129X1/SvJ	abnormal synaptic transmission	J:77047
	environmentally induced seizures	J:38206
	increased susceptibility to pharmacologically induced seizures	J:38206
	tonic-clonic seizures	J:38206
Kcnj6tm1Stf/Kcnj6wv involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cerebellar Purkinje cell layer	J:38206
	thin cerebellar granule layer	J:38206
Kcnj6wv/Kcnj6+ B6CBA Aw-J/A-Kcnj6wv	abnormal male germ cell morphology	J:23163
	abnormal seminiferous tubule epithelium morphology	J:23163
	abnormal sperm motility	J:23163
	abnormal spermatid morphology	J:23163
	abnormal spermatogenesis	J:23163
	oligozoospermia	J:23163
Kcnj6wv/Kcnj6+ B6CBACa Aw-J/A-Kcnj6wv/J	abnormal cerebellar Purkinje cell layer	J:72069
	abnormal Purkinje cell dendrite morphology	J:72069
	abnormal Purkinje cell morphology	J:72069
	delaminated Purkinje cell layer	J:72069
Kcnj6wv/Kcnj6+ involves: C57BL/6 * CBA/CaGnLe	abnormal cerebellar granule layer morphology	J:46842
	abnormal cerebellar Purkinje cell layer	J:46842
	abnormal cerebellum morphology	J:18348
	small cerebellum	J:46842
Kcnj6wv/Kcnj6+ involves: C57BL/6J	abnormal cell migration	J:16025
	abnormal cerebellar molecular layer	J:16025
	abnormal cerebellum morphology	J:16025
	abnormal cerebellum vermis morphology	J:16025
	abnormal locomotor behavior	J:38206
	abnormal substantia nigra pars compacta morphology	J:38206
	increased apoptosis	J:16025
	male infertility	J:38206
Kcnj6wv/Kcnj6wv B6CBA Aw-J/A-Kcnj6wv	abnormal ion homeostasis	J:106298
	abnormal male germ cell morphology	J:23163
	abnormal seminiferous tubule epithelium morphology	J:23163
	abnormal seminiferous tubule morphology	J:23163
	abnormal Sertoli cell morphology	J:23163
	abnormal sperm motility	J:23163
	abnormal spermatid morphology	J:106298
	abnormal spermatogenesis	J:23163
	globozoospermia	J:23163
	oligozoospermia	J:23163
Kcnj6wv/Kcnj6wv B6CBACa Aw-J/A-Kcnj6wv/J	abnormal cerebellar cortex morphology	J:72069
	abnormal cerebellar lobule formation	J:72069
	abnormal cerebellar Purkinje cell layer	J:72069
	abnormal locomotor activation	J:6717
	abnormal nervous system morphology	J:6717
	abnormal Purkinje cell dendrite morphology	J:72069
	abnormal substantia nigra pars compacta morphology	J:6717
	ataxia	J:72069
	decreased body weight	J:72069
	decreased dopamine level	J:6717
	decreased dopaminergic neuron number	J:6717
	ectopic Purkinje cell	J:72069
	normal homeostasis/metabolism phenotype	J:29151
Kcnj6wv/Kcnj6wv C57BL/6J-Kcnj6wv	abnormal cerebellar granule cell morphology	J:15542
	abnormal cerebellar granule layer morphology	J:30520
	abnormal cerebellar molecular layer	J:30520
	abnormal cerebellar Purkinje cell layer	J:30520
	abnormal cerebellum development	J:30520
	abnormal cerebellum external granule cell layer morphology	J:30520
	abnormal gait	J:30520
	abnormal maternal nurturing	J:30520
	abnormal motor capabilities/coordination/movement	J:13422
	abnormal motor coordination/balance	J:30520
	absent cerebellar lobules	J:30520
	absent cerebellum fissure	J:30520
	decreased body size	J:30520
	decreased body weight	J:30520
	decreased food intake	J:30520
	impaired righting response	J:30520
	increased Purkinje cell number	J:30520
	induced hyperactivity	J:30520
	lethality at weaning, incomplete penetrance	J:30520
	premature death	J:13422, J:30520
	reduced female fertility	J:30520
	reduced male fertility	J:30520
	small cerebellum	J:30520
	tonic-clonic seizures	J:30520
	tremors	J:30520
	weaving	J:30520
Kcnj6wv/Kcnj6wv involves: C57BL/6	abnormal cerebellar granule cell morphology	J:35792
	abnormal CNS synaptic transmission	J:35792
	abnormal cochlear VIII nucleus morphology	J:121314
	abnormal synaptic glutamate release	J:6875
	abnormal synaptic neurotransmitter level	J:6875
	decreased Purkinje cell number	J:121314
	decreased taurine level	J:6875
	small cerebellum	J:6875
Kcnj6wv/Kcnj6wv involves: C57BL/6 * CBA/CaGnLe	abnormal cerebellar granule layer morphology	J:46842
	abnormal cerebellar molecular layer	J:46842
	abnormal cerebellum external granule cell layer morphology	J:46842
	abnormal epididymis morphology	J:18348
	abnormal seminiferous tubule morphology	J:18348
	abnormal testis morphology	J:18348
	ataxia	J:18348, J:46842
	azoospermia	J:18348
	hypotonia	J:18348
	impaired righting response	J:18348
	increased apoptosis	J:46842
	increased noradrenaline level	J:164122
	male infertility	J:18348
	retropulsion	J:18348
	seminiferous tubule degeneration	J:18348, J:46842
	small cerebellum	J:18348, J:46842, J:164122
	tremors	J:18348
Kcnj6wv/Kcnj6wv involves: C57BL/6J	abnormal cell migration	J:16025
	abnormal cerebellar cortex morphology	J:5315
	abnormal cerebellar granule layer morphology	J:5315, J:16025
	abnormal cerebellar molecular layer	J:16025
	abnormal cerebellar Purkinje cell layer	J:5315
	abnormal cerebellum morphology	J:5315, J:16025
	abnormal cerebellum vermis morphology	J:16025
	abnormal Purkinje cell morphology	J:5315
	increased apoptosis	J:16025
Kcnj6wv/Kcnj6wv involves: C57BL/6J * CBA	abnormal hippocampal mossy fiber morphology	J:30108
	abnormal hippocampus pyramidal cell layer	J:30108
	ectopic hippocampus pyramidal cells	J:30108