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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Adra1a
adrenergic receptor, alpha 1a
MGI:104773
26 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Adra1atm1Pcs/Adra1atm1Pcs
Adra1btm1Cta/Adra1btm1Cta
B6.129-Adra1btm1Cta Adra1atm1Pcs
small heart J:83876
small myocardial fiber J:83876
Adra1atm1Pcs/Adra1atm1Pcs
Adra1btm1Cta/Adra1btm1Cta
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N
abnormal cardiac muscle contractility J:102648
abnormal cardiovascular system physiology J:83876
abnormal heart size J:83876
abnormal myocardial fiber physiology J:102648
congestive heart failure J:83876
decreased cardiac output J:83876
decreased cardiac stroke volume J:83876
decreased heart rate J:83876
decreased heart weight J:83876
enlarged kidney J:83876
impaired exercise endurance J:83876
increased cardiac muscle contractility J:83876
increased left ventricle developed pressure J:102648
increased response of heart to induced stress J:83876
increased sensitivity to induced morbidity/mortality J:83876
small heart J:83876
small myocardial fiber J:83876
Tg(Myh6-Adra1a)A1A1Rmgr/0
FVB/N-Tg(Myh6-Adra1a)A1A1Rmgr
abnormal cardiac muscle relaxation J:108879
cardiac fibrosis J:108867
decreased left ventricle diastolic pressure J:108879
decreased QRS amplitude J:108867
increased cardiac muscle contractility J:108879
increased heart rate J:108867, J:108879
increased ventricle muscle contractility J:108867
premature death J:108867
Tg(Myh6-Adra1a)A1A4Rmgr/0
FVB/N-Tg(Myh6-Adra1a)A1A4Rmgr
cardiac fibrosis J:108867
increased cardiac muscle contractility J:108879
increased cardiomyocyte apoptosis J:108867
increased ventricle muscle contractility J:108867
myocardial fiber degeneration J:108867
premature death J:108867

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory