Cdkn2b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cdkn2b
cyclin dependent kinase inhibitor 2B
MGI:104737

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cdkn2b^tm1Bbd/Cdkn2b^tm1Bbd involves: 129S1/Sv * C57BL/6	abnormal cell physiology	J:63299
	abnormal lymph node germinal center morphology	J:63299
	abnormal lymph node secondary follicle morphology	J:63299
	abnormal lymphocyte morphology	J:63299
	abnormal spleen marginal zone morphology	J:63299
	abnormal spleen morphology	J:63299
	extramedullary hematopoiesis	J:63299
	increased adenocarcinoma incidence	J:63299
	increased fibroblast proliferation	J:63299
	increased mature B cell number	J:63299
	increased sarcoma incidence	J:63299
	increased tumor incidence	J:63299
	lymph node hyperplasia	J:63299
	lymphoid hyperplasia	J:63299
	premature death	J:63299
	spleen hyperplasia	J:63299
Cdkn2b^tm1Wff/Cdkn2b^tm1Wff Lyz2^tm1(cre)Ifo/Lyz2⁺ involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6	abnormal common myeloid progenitor cell morphology	J:163498
	abnormal megakaryocyte progenitor cell morphology	J:163498
	decreased erythroid progenitor cell number	J:163498
	increased monocyte cell number	J:163498
	myeloid hyperplasia	J:163498

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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