Ccr3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccr3
C-C motif chemokine receptor 3
MGI:104616

23 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ccr3^{em1(IMPC)Ccpcz}/Ccr3^{em1(IMPC)Ccpcz} C57BL/6NCrl-Ccr3^{em1(IMPC)Ccpcz}/Ccpcz	abnormal cornea morphology	J:211773
	abnormal digit morphology	J:211773
	abnormal heart morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal thymus morphology	J:211773
	enlarged heart	J:211773
	enlarged spleen	J:211773
	enlarged thymus	J:211773
Ccr3^tm1Cge/Ccr3^tm1Cge involves: 129S4/SvJae * BALB/c	abnormal airway responsiveness	J:75347
	abnormal eosinophil cell number	J:74509
	abnormal eosinophil physiology	J:74509, J:75347
	abnormal hemostasis	J:115273
	abnormal mast cell physiology	J:74509
	abnormal respiratory system physiology	J:115273
	decreased circulating interleukin-4 level	J:115273
	decreased eosinophil cell number	J:74509, J:75347, J:115273
	decreased monocyte cell number	J:115273
	normal hematopoietic system phenotype	J:75347
	impaired eosinophil chemotaxis	J:74509
	impaired eosinophil recruitment	J:74509, J:75347
	increased airway responsiveness	J:74509
	increased eosinophil cell number	J:74509
	increased mast cell degranulation	J:74509

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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