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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ptprj
protein tyrosine phosphatase receptor type J
MGI:104574
34 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
PtprjScc1-r/PtprjScc1-r
involves: BALB/cHeA * STS/A
decreased incidence of tumors by chemical induction J:31355
PtprjScc1-s/?
involves: BALB/cHeA * STS/A
increased tumor incidence J:31355, J:36996
PtprjScc1-s/?
involves: BALB/cJ * STS/A
increased tumor incidence J:44
Ptprjtm1.2Weis/Ptprjtm1.2Weis
involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
abnormal B cell differentiation J:131736
abnormal splenic cell ratio J:131736
increased B-2 B cell number J:131736
increased marginal zone B cell number J:131736
infertility J:131736
Ptprjtm1Fus/Ptprjtm1Fus
involves: 129X1/SvJ * C57BL/6J
normal neoplasm J:112807
no abnormal phenotype detected J:112807
Ptprjtm1Taka/Ptprj+
involves: 129S6/SvEvTac * C57BL/6
embryonic lethality during organogenesis, incomplete penetrance J:82356
Ptprjtm1Taka/Ptprjtm1Taka
involves: 129S6/SvEvTac
abnormal dorsal aorta morphology J:82356
abnormal endocardium morphology J:82356
abnormal heart development J:82356
abnormal intersomitic vessel morphology J:82356
abnormal myocardial trabeculae morphology J:82356
abnormal pericardial cavity morphology J:82356
abnormal pericyte morphology J:82356
abnormal vascular branching morphogenesis J:82356
abnormal vascular development J:82356
abnormal vascular endothelial cell morphology J:82356
abnormal vascular smooth muscle morphology J:82356
abnormal vitelline vascular remodeling J:82356
abnormal vitelline vasculature morphology J:82356
absent atrioventricular cushions J:82356
decreased embryo size J:82356
delayed heart looping J:82356
distended pericardium J:82356
embryonic growth retardation J:82356
embryonic lethality during organogenesis, complete penetrance J:82356
failure of vascular branching J:82356
increased vascular endothelial cell number J:82356
microcephaly J:82356
thin myocardium J:82356
vascular smooth muscle hypoplasia J:82356

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory