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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nog
noggin
MGI:104327
142 phenotypes from 5 alleles in 18 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Myf5tm3(cre)Sor/Myf5+
Tg(CAG-Nog)1Ych/0
involves: 129S4/SvJaeSor 		abnormal levator veli palatini muscle morphology J:310908
abnormal palatopharyngeus muscle morphology J:310908
abnormal soft palate muscle morphology J:310908
abnormal superior pharyngeal constrictor muscle morphology J:310908
abnormal tensor veli palatini muscle morphology J:310908
cleft soft palate J:310908
Nogem1(IMPC)Mbp/Nog+
C57BL/6N-Nogem1(IMPC)Mbp/MbpMmucd 		abnormal bone structure J:211773
abnormal caudal vertebrae morphology J:211773
abnormal kidney morphology J:211773
abnormal placenta morphology J:211773
abnormal snout morphology J:211773
edema J:211773
increased circulating alkaline phosphatase level J:211773
small kidney J:211773
Nogem1(IMPC)Mbp/Nogem1(IMPC)Mbp
C57BL/6N-Nogem1(IMPC)Mbp/MbpMmucd 		abnormal blood vessel morphology J:211773
abnormal embryo turning J:211773
abnormal forebrain development J:211773
abnormal heart morphology J:211773
abnormal neural tube closure J:211773
abnormal neural tube morphology J:211773
abnormal optic vesicle formation J:211773
abnormal pharyngeal arch morphology J:211773
abnormal somite shape J:211773
abnormal visceral yolk sac morphology J:211773
abnormal vitelline vasculature morphology J:211773
embryonic growth retardation J:211773
preweaning lethality, complete penetrance J:211773
Nogtm1.1Rmh/Nogtm1.1Rmh
Tmem163Tg(ACTB-cre)2Mrt/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL 		abnormal cartilage development J:169133
abnormal cartilage morphology J:169133
abnormal rib morphology J:169133
abnormal skeleton development J:169133
abnormal vertebrae morphology J:169133
Nogtm1Amc/Nog+
B6.129S1-Nogtm1Amc 		abnormal rib morphology J:108573
fused synovial joints J:108573
kinked tail J:108573
small thoracic cage J:108573
Nogtm1Amc/Nog+
D1.129S1-Nogtm1Amc 		abnormal middle ear morphology J:132023
abnormal middle ear ossicle morphology J:132023
abnormal rib morphology J:108573
abnormal stapes morphology J:132023
abnormal styloid process morphology J:132023
conductive hearing loss J:132023
fused synovial joints J:108573
impaired hearing J:132023
increased or absent threshold for auditory brainstem response J:132023
kinked tail J:108573
small thoracic cage J:108573
Nogtm1Amc/Nog+
involves: 129S1/Sv * C57BL/6J * ICR 		decreased prostate gland ventral lobe weight J:130204
Nogtm1Amc/Nog+
involves: 129S1/Sv * CD-1 		abnormal axial skeleton morphology J:108573
abnormal rib morphology J:108573
fused synovial joints J:108573
kinked tail J:108573
kyphosis J:108573
small thoracic cage J:108573
Nogtm1Amc/Nog+
involves: C57BL/6J * FVB 		normal hearing/vestibular/ear phenotype J:132023
Nogtm1Amc/Nogtm1Amc
B6.129S1-Nogtm1Amc 		abnormal incus morphology J:132023
abnormal malleus morphology J:132023
fusion of middle ear ossicles J:132023
lethality throughout fetal growth and development, complete penetrance J:108573
small limb buds J:108573
Nogtm1Amc/Nogtm1Amc
D1.129S1-Nogtm1Amc 		exencephaly J:108573
perinatal lethality J:108573
Nogtm1Amc/Nogtm1Amc
either: 129/Sv or (involves: 129S1/Sv * C57BL/6J) 		abnormal axial skeleton morphology J:47724
abnormal ear development J:47724
abnormal eye development J:47724
abnormal hair follicle development J:59676
abnormal neural tube morphology J:47724
abnormal notochord morphology J:47724
abnormal rostral-caudal patterning of the somites J:47724
abnormal somite development J:47724
abnormal spinal cord morphology J:47724
decreased embryo size J:47724
decreased somite size J:47724
incomplete rostral neuropore closure J:47724
perinatal lethality, complete penetrance J:47724
short limbs J:47724
vestigial tail J:47724
Nogtm1Amc/Nogtm1Amc
either: (involves: 129S1/Sv * C57BL/6) or (involves: 129S1/Sv * CD-1 * ICR) 		abnormal esophagus development J:118341
abnormal foregut morphology J:118341
abnormal neural tube morphology J:118341
abnormal notochord morphology J:118341
esophageal atresia J:118341
esophagus stenosis J:118341
incomplete rostral neuropore closure J:118341
open neural tube J:118341
tracheoesophageal fistula J:118341
Nogtm1Amc/Nogtm1Amc
either: (involves: 129S1/Sv * CD-1) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		abnormal diencephalon morphology J:121318
abnormal head morphology J:121318
abnormal neural tube morphology J:121318
abnormal pituitary gland development J:121318
abnormal pituitary gland physiology J:121318
abnormal Rathke's pouch apoptosis J:121318
abnormal Rathke's pouch development J:121318
absent adenohypophysis J:121318
absent pituitary gland J:121318
absent pituitary infundibular stalk J:121318
absent Rathke's pouch J:121318
Nogtm1Amc/Nogtm1Amc
involves: 129S1/Sv 		abnormal axial skeleton morphology J:110617
abnormal basicranium morphology J:74136
abnormal frontal bone morphology J:74136
abnormal interparietal bone morphology J:74136
abnormal lung development J:83697
abnormal lung morphology J:83697
abnormal neural plate morphology J:110617
abnormal neural tube closure J:74136, J:110617
abnormal neural tube morphology J:110617
abnormal occipital bone morphology J:74136
abnormal parietal bone morphology J:74136
abnormal right lung morphology J:83697
abnormal somite development J:110617
abnormal spinal cord morphology J:110617
abnormal vertebral arch morphology J:110617
absent tail J:74136
absent vertebral arch J:110617
exencephaly J:74136, J:110617
incomplete rostral neuropore closure J:110617
increased apoptosis J:110617
kinked neural tube J:110617
open neural tube J:74136
perinatal lethality, complete penetrance J:74136, J:110617
short limbs J:74136
spina bifida occulta J:110617
wavy neural tube J:110617
Nogtm1Amc/Nogtm1Amc
involves: 129S1/Sv * C57BL/6J * FVB/N 		abnormal cochlea morphology J:156945
decreased cochlea coiling J:156945
increased cochlear inner hair cell number J:156945
increased cochlear outer hair cell number J:156945
Nogtm1Amc/Nogtm1Amc
involves: 129S1/Sv * C57BL/6J * ICR 		abnormal male reproductive system morphology J:130204
abnormal primitive urogenital sinus morphology J:130204
abnormal prostate gland development J:130204
abnormal prostate gland morphology J:130204
abnormal septation of the cloaca J:130204
abnormal urethra morphology J:130204
abnormal urinary system development J:130204
absent bulbourethral gland J:130204
absent tail J:130204
anal atresia J:130204
cryptorchism J:130204
pelvic kidney J:130204
Nogtm1Amc/Nogtm1Amc
involves: 129S1/Sv * CD-1 		abnormal bone mineralization J:108573
abnormal hair follicle development J:108573
abnormal limb bud morphology J:108573
abnormal limb morphology J:108573
abnormal muscle fiber morphology J:108573
abnormal muscle morphology J:108573
decreased fetal size J:108573
edema J:108573
exencephaly J:108573
fused synovial joints J:108573
hematoma J:108573
perinatal lethality J:108573
vestigial tail J:108573
Nogtm1Amc/Nogtm1Amc
involves: C57BL/6 		abnormal craniofacial morphology J:110617
abnormal neural tube morphology J:110617
abnormal skeleton morphology J:110617
exencephaly J:110617
perinatal lethality, complete penetrance J:110617
short face J:110617
Osr2tm2(cre)Jian/Osr2+
Tg(CAG-Nog)1Ych/0
involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6 		abnormal mandible morphology J:149232
cleft palate J:149232
Osr2tm5(cre)Jian/Osr2+
Tg(CAG-Nog)1Ych/0
Not Specified 		abnormal palatine aponeurosis morphology J:310908
abnormal palatopharyngeus muscle morphology J:310908
abnormal secondary palate development J:310908
abnormal superior pharyngeal constrictor muscle morphology J:310908
palatal shelf hypoplasia J:310908
small levator veli palatini muscle J:310908
small tensor veli palatini muscle J:310908
Tg(Krt14-Nog)#Jake/0
FVB-Tg(Krt14-Nog)#Jake 		abnormal apical ectodermal ridge morphology J:78767
abnormal coat/ hair morphology J:78767
abnormal interdigital cell death J:78767
abnormal vibrissa morphology J:78767
brachydactyly J:78767
camptodactyly J:78767
interdigital webbing J:78767
polysyndactyly J:78767
postaxial polydactyly J:78767
preaxial polydactyly J:78767
slow postnatal weight gain J:78767
syndactyly J:78767
Tg(Krt14-Nog)#Jake/0
involves: BALB/c * C57BL/6 * FVB 		abnormal interdigital cell death J:78767
brachydactyly J:78767
camptodactyly J:78767
interdigital webbing J:78767
polysyndactyly J:78767
postaxial polydactyly J:78767
preaxial polydactyly J:78767
syndactyly J:78767
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory