43 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ednratm7(Hand2)Hku/Ednra+ chimera involves: 129 * C57BL/6 * ICR	abnormal gonial bone morphology	J:224515
	abnormal Meckel's cartilage morphology	J:224515
	abnormal temporal bone squamous part morphology	J:224515
	absent gonial bone	J:224515
	absent temporal bone squamous part	J:224515
	perinatal lethality, complete penetrance	J:224515
	upper jaw to lower jaw transformation	J:224515
Gli3Xt-J/Gli3Xt-J Hand2tm1.1Zllr/Hand2tm1.2Zllr Tg(Prrx1-cre)1Cjt/0 involves: 129 * BALB/cJ * C3H/HeJ * C57BL/6 * SJL	abnormal autopod morphology	J:159210
	abnormal forelimb stylopod morphology	J:159210
	abnormal forelimb zeugopod morphology	J:159210
	abnormal limb development	J:159210
	postaxial polydactyly	J:159210
	preaxial polydactyly	J:159210
Hand1tm2.1(Hand1)Abfi/Hand1tm2.1(Hand1)Abfi Hand2tm1Dsr/Hand2tm1Dsr involves: 129S7/SvEvBrd	abnormal cardiovascular system morphology	J:164028
	abnormal rostral-caudal axis patterning	J:164028
	decreased embryo size	J:164028
	thin ventricular wall	J:164028
Hand2tm1.2Zllr/Hand2+ Is(In8B2-8B3.1;6C1)1Tshir/0 involves: 129 * C57BL/6 * C57BL/10 * NZB * wild-derived	normal limbs/digits/tail phenotype	J:198239
Hand2tm1.2Zllr/Hand2tm1.2Zllr Is(In8B2-8B3.1;6C1)1Tshir/Is(In8B2-8B3.1;6C1)1Tshir involves: 129 * C57BL/6 * C57BL/10 * NZB * wild-derived	abnormal cervical vertebrae morphology	J:198239
	abnormal craniofacial morphology	J:198239
	normal cardiovascular system phenotype	J:198239
	clavicle hypoplasia	J:198239
	normal limbs/digits/tail phenotype	J:198239
	microcephaly	J:198239
Hand2tm1Dsr/Hand2+ Nkx2-5tm1Wehi/Nkx2-5+ involves: C57BL/6	normal mortality/aging	J:72600
Hand2tm1Dsr/Hand2tm1Dsr Nkx2-5tm1Wehi/Nkx2-5tm1Wehi involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6	abnormal blood vessel morphology	J:72600
	abnormal cardiac outflow tract development	J:72600
	abnormal heart atrium morphology	J:72600
	abnormal sinus venosus morphology	J:72600
	absent myocardial trabeculae	J:72600
	congestive heart failure	J:72600
	embryonic lethality during organogenesis, complete penetrance	J:72600
	pericardial effusion	J:72600
	ventricular hypoplasia	J:72600
Hand2tm1Dsr/Hand2tm2.1Dsr Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ Isl1tm1(cre)Tmj/Isl1+ involves: 129S4/SvJaeSor * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6	abnormal heart development	J:169213
Hand2tm1Dsr/Hand2tm2.1Dsr Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ Tg(Tbx1-cre)#Dsr/0 involves: 129 * 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6	abnormal cardiac outflow tract development	J:169213
	decreased heart right ventricle size	J:169213
Rr133tm1Eno/Rr133+ Hand2tm2Eno/Hand2tm2Eno involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal mandibular angle morphology	J:146638
	abnormal secondary palate development	J:146638
	absent suckling reflex	J:146638
	cleft secondary palate	J:146638
	decreased tympanic ring size	J:146638
	failure of palatal shelf elevation	J:146638
	mandible hypoplasia	J:146638
	neonatal lethality, complete penetrance	J:146638