Hand2tm1.1Majh/Hand2tm1.1Majh
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/SvImJ * C57BL/6J * CBA/J * DBA/2
|
abnormal craniofacial bone morphology |
J:137726
|
|
abnormal enteric ganglia morphology |
J:138032
|
|
abnormal enteric nervous system morphology |
J:138032
|
|
abnormal enteric neuron morphology |
J:138032
|
|
abnormal heart development |
J:137726
|
|
abnormal neuron differentiation |
J:137726
|
|
abnormal sympathetic ganglion morphology |
J:137726
|
|
decreased embryo size |
J:137726
|
|
embryonic lethality during organogenesis, complete penetrance |
J:137726
|
|
normal
nervous system phenotype |
J:137726
|
|
short mandible |
J:137726
|
Hand2tm1.1Zllr/Hand2tm1.2Zllr
Tg(Prrx1-cre)1Cjt/0
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6 * SJL
|
abnormal autopod morphology |
J:159210
|
|
abnormal digit development |
J:159210
|
|
abnormal forelimb zeugopod morphology |
J:159210
|
|
abnormal hindlimb morphology |
J:159210
|
|
abnormal interdigital cell death |
J:159210
|
|
increased apoptosis |
J:159210
|
Hand2tm1.2Zllr/Hand2tm1.2Zllr
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6 * SJL
|
abnormal pharyngeal arch artery morphology |
J:159210
|
|
dilated aortic sac |
J:159210
|
|
distended pericardium |
J:159210
|
|
embryonic growth retardation |
J:159210
|
|
increased embryonic tissue cell apoptosis |
J:159210
|
Hand2tm1Cse/Hand2+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * C57BL/6J * CBA/J
|
aberrant origin of the right subclavian artery |
J:155265
|
|
abnormal cell cycle |
J:155265
|
|
abnormal fetal cardiomyocyte proliferation |
J:155265
|
|
abnormal myocardial trabeculae morphology |
J:155265
|
|
abnormal thymus development |
J:155265
|
|
normal
embryo phenotype |
J:155265
|
|
heart right ventricle hypertrophy |
J:155265
|
|
interrupted aortic arch |
J:155265
|
|
lethality throughout fetal growth and development, complete penetrance |
J:155265
|
|
perimembraneous ventricular septal defect |
J:155265
|
|
pulmonary artery stenosis |
J:155265
|
|
retroesophageal right subclavian artery |
J:155265
|
Hand2tm1Cse/Hand2+
Tg(Tnnt2-cre)5Blh/0
involves: 129S1/Sv * C57BL/6J * DBA/2
|
abnormal cardiac outflow tract development |
J:155265
|
|
abnormal heart ventricle morphology |
J:155265
|
|
decreased heart right ventricle size |
J:155265
|
|
embryonic lethality during organogenesis, complete penetrance |
J:155265
|
Hand2tm1Cse/Hand2+
Tg(Hoxb6-cre)#Mku/0
involves: 129S1/Sv * FVB/N
|
abnormal limb development |
J:155265
|
|
normal
cardiovascular system phenotype |
J:155265
|
|
normal
embryo phenotype |
J:155265
|
|
normal
mortality/aging |
J:155265
|
Hand2tm1Cse/Hand2+
Tg(DBH-cre)1Cse/0
involves: 129S1/Sv
|
embryonic lethality during organogenesis, complete penetrance |
J:155265
|
|
liver vascular congestion |
J:155265
|
|
visceral vascular congestion |
J:155265
|
Hand2tm1Cse/Hand2tm1Cse
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6 * CBA
|
normal
craniofacial phenotype |
J:149232
|
Hand2tm1Cse/Hand2tm1Cse
Osr2tm2(cre)Jian/Osr2+
involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6
|
mandible hypoplasia |
J:149232
|
Hand2tm1Cse/Hand2tm1Cse
Tg(Pitx2-cre)1Ych/0
involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6
|
cleft secondary palate |
J:149232
|
|
failure of palatal shelf elevation |
J:149232
|
Hand2tm1Cse/Hand2tm1Dsr
involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6
|
abnormal palatal shelf elevation |
J:149232
|
|
abnormal primary and secondary palatal fusion |
J:122604
|
|
abnormal suckling behavior |
J:122604
|
|
cleft secondary palate |
J:122604
|
|
decreased palatal shelf size |
J:149232
|
|
neonatal lethality, complete penetrance |
J:122604
|
|
palatal shelves fail to meet at midline |
J:149232
|
|
tongue hypoplasia |
J:149232
|
Hand2tm1Cse/Hand2tm1Dsr
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6 * CBA
|
abnormal adrenergic neuron morphology |
J:122604
|
|
abnormal blood circulation |
J:122604
|
|
abnormal enzyme/coenzyme level |
J:122604
|
|
embryonic lethality during organogenesis, complete penetrance |
J:122604
|
|
normal
nervous system phenotype |
J:122604
|
|
visceral vascular congestion |
J:122604
|
Hand2tm1Dsr/Hand2tm1Dsr
involves: 129 * 129S7/SvEvBrd * C57BL/6
|
heart right ventricle hypoplasia |
J:169213
|
|
increased apoptosis |
J:169213
|
Hand2tm1Dsr/Hand2tm1Dsr
involves: 129S7/SvEvBrd
|
abnormal cardiac outflow tract development |
J:40768
|
|
abnormal first pharyngeal arch artery morphology |
J:40768
|
|
abnormal forelimb bud morphology |
J:62028
|
|
abnormal forelimb morphology |
J:62028
|
|
abnormal heart looping |
J:40768
|
|
abnormal heart ventricle morphology |
J:40768
|
|
abnormal pharyngeal arch artery morphology |
J:40768
|
|
absent heart right ventricle |
J:40768
|
|
absent myocardial trabeculae |
J:40768
|
|
absent second pharyngeal arch artery |
J:40768
|
|
absent trabeculae carneae |
J:40768
|
|
congestive heart failure |
J:40768
|
|
decreased cardiac muscle contractility |
J:40768
|
|
decreased embryo size |
J:40768
|
|
decreased somite size |
J:62028
|
|
dilated aortic sac |
J:40768
|
|
edema |
J:62028
|
|
embryonic growth retardation |
J:40768
|
|
embryonic lethality during organogenesis, complete penetrance |
J:40768
|
|
pericardial effusion |
J:40768
|
|
poor circulation |
J:62028
|
|
small forelimb buds |
J:62028
|
|
thin myocardium |
J:40768
|
Hand2tm1Dsr/Hand2tm1Dsr
involves: 129S7/SvEvBrd * C57BL/6
|
absent pharyngeal arches |
J:49658
|
|
congestive heart failure |
J:49658
|
|
decreased embryo size |
J:49658
|
|
embryonic growth retardation |
J:49658
|
|
embryonic lethality during organogenesis, complete penetrance |
J:49658
|
|
incomplete somite formation |
J:49658
|
|
increased apoptosis |
J:49658
|
|
pharyngeal arch hypoplasia |
J:49658
|
Hand2tm1Dsr/Hand2tm2.1Dsr
Isl1tm1(cre)Tmj/Isl1+
involves: 129 * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
|
abnormal cardiac outflow tract development |
J:169213
|
|
embryonic lethality during organogenesis, complete penetrance |
J:169213
|
|
heart right ventricle hypoplasia |
J:169213
|
|
increased apoptosis |
J:169213
|
Hand2tm1Dsr/Hand2tm2.1Dsr
Tg(Mef2c-cre)#Blk/0
involves: 129 * 129S7/SvEvBrd * C57BL/6
|
abnormal tricuspid valve morphology |
J:169213
|
|
decreased heart right ventricle size |
J:169213
|
|
embryonic lethality during organogenesis, complete penetrance |
J:169213
|
|
heart right ventricle hypoplasia |
J:169213
|
|
persistent truncus arteriosus |
J:169213
|
|
thin myocardium |
J:169213
|
|
ventricular septal defect |
J:169213
|
Hand2tm1Dsr/Hand2tm2.1Dsr
Tg(Nkx2-5-cre)9Eno/0
involves: 129 * 129S7/SvEvBrd * C57BL/6
|
decreased heart left ventricle size |
J:169213
|
|
decreased heart right ventricle size |
J:169213
|
|
embryonic lethality during organogenesis, complete penetrance |
J:169213
|
Hand2tm1Dsr/Hand2tm2.1Dsr
Tg(Tbx1-cre)#Dsr/0
involves: 129 * 129S7/SvEvBrd * C57BL/6
|
abnormal cardiac outflow tract development |
J:169213
|
|
decreased heart right ventricle size |
J:169213
|
|
lethality throughout fetal growth and development, complete penetrance |
J:169213
|
Hand2tm1Majh/Hand2tm1Majh
involves: 129S1/SvImJ
|
abnormal craniofacial bone morphology |
J:137726
|
|
abnormal heart development |
J:137726
|
|
abnormal suckling behavior |
J:137726
|
|
cleft secondary palate |
J:137726
|
|
decreased embryo size |
J:137726
|
|
embryonic lethality during organogenesis, complete penetrance |
J:137726
|
|
normal
nervous system phenotype |
J:137726
|
|
short mandible |
J:137726
|
Hand2tm2.1Dsr/Hand2tm2.1Dsr
involves: 129 * C57BL/6
|
no abnormal phenotype detected |
J:169213
|
Hand2tm2Eno/Hand2tm2Eno
involves: 129S6/SvEvTac * C57BL/6 * SJL
|
abnormal apical ectodermal ridge morphology |
J:146638
|
|
abnormal atrioventricular cushion morphology |
J:146638
|
|
abnormal cardiac outflow tract development |
J:146638
|
|
abnormal facial morphology |
J:146638
|
|
abnormal first pharyngeal arch morphology |
J:146638
|
|
abnormal heart left ventricle morphology |
J:146638
|
|
abnormal heart right ventricle morphology |
J:146638
|
|
abnormal interventricular septum morphology |
J:146638
|
|
abnormal jaw morphology |
J:146638
|
|
abnormal limb bud morphology |
J:146638
|
|
decreased heart right ventricle size |
J:146638
|
|
dilated heart left ventricle |
J:146638
|
|
embryonic lethality during organogenesis, complete penetrance |
J:146638
|
|
increased atrioventricular cushion size |
J:146638
|
Tg(Hand2)#Tshir/0
Not Specified
|
abnormal pollex morphology |
J:198239
|
|
decreased lumbar vertebrae number |
J:198239
|
|
hemimelia |
J:198239
|
Tg(Prrx1-Hand2)1Eno/0
involves: C57BL/6 * CBA
|
polydactyly |
J:80030
|
Tg(Prrx1-Hand2)2Eno/0
involves: C57BL/6 * CBA
|
abnormal forelimb zeugopod morphology |
J:80030
|
|
abnormal hindlimb zeugopod morphology |
J:80030
|
|
abnormal limb bone morphology |
J:80030
|
|
polydactyly |
J:80030
|
|
short limbs |
J:80030
|
Tg(Prrx1-Hand2)3Eno/0
involves: C57BL/6 * CBA
|
oligodactyly |
J:80030
|
|
polydactyly |
J:80030
|
|
short limbs |
J:80030
|
Tg(Prrx1-Hand2)4Eno/0
involves: C57BL/6 * CBA
|
normal
limbs/digits/tail phenotype |
J:80030
|
Tg(Prrx1-Hand2)5Eno/0
involves: C57BL/6 * CBA
|
abnormal forelimb zeugopod morphology |
J:80030
|
|
abnormal hindlimb zeugopod morphology |
J:80030
|
|
abnormal limb bone morphology |
J:80030
|
|
polydactyly |
J:80030
|
Tg(Prrx1-Hand2)6Eno/0
involves: C57BL/6 * CBA
|
abnormal forelimb zeugopod morphology |
J:80030
|
|
abnormal hindlimb zeugopod morphology |
J:80030
|
|
abnormal limb bone morphology |
J:80030
|
|
polydactyly |
J:80030
|
Tg(Prrx1-Hand2)7Eno/0
involves: C57BL/6 * CBA
|
normal
limbs/digits/tail phenotype |
J:80030
|
Tg(Prrx1-Hand2)8Eno/0
involves: C57BL/6 * CBA
|
normal
limbs/digits/tail phenotype |
J:80030
|
Tg(Prrx1-Hand2/VP16)1Eno/0
involves: C57BL/6 * CBA
|
polydactyly |
J:80030
|
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