Xpc Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Xpc
xeroderma pigmentosum, complementation group C
MGI:103557

11 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Xpc^tm1Brd/Xpc^tm1Brd involves: 129S7/SvEvBrd * C57BL	abnormal cell physiology	J:28708
	increased incidence of tumors by UV-induction	J:28708
	increased sensitivity to skin irradiation	J:28708
	photosensitivity	J:28708
Xpc^tm1Ecf/Xpc⁺ involves: 129 * SKH1	increased sensitivity to skin irradiation	J:120007
Xpc^tm1Ecf/Xpc^tm1Ecf involves: 129	increased cellular sensitivity to ultraviolet irradiation	J:80212
Xpc^tm1Ecf/Xpc^tm1Ecf involves: 129	oxidative stress	J:70397
Xpc^tm1Ecf/Xpc^tm1Ecf involves: 129 * C57BL/6	increased lung adenocarcinoma incidence	J:101421
	increased lung adenoma incidence	J:101421
	increased lung tumor incidence	J:101421
Xpc^tm1Ecf/Xpc^tm1Ecf involves: 129 * SKH1	abnormal hair follicle morphology	J:120007
	epidermal hyperplasia	J:120007
	increased sensitivity to skin irradiation	J:120007

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23