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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Nfatc3
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
MGI:103296
23 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Nfatc3tm1.1Grc/Nfatc3tm1.1Grc
involves: C57BL/6
decreased litter size J:141917
decreased survivor rate J:141917
normal immune system phenotype J:141917
lymph node hypoplasia J:141917
prenatal lethality, incomplete penetrance J:141917
Nfatc3tm1b(EUCOMM)Hmgu/Nfatc3+
C57BL/6N-Nfatc3tm1b(EUCOMM)Hmgu/Ieg
abnormal lens morphology J:211773
Nfatc3tm1b(EUCOMM)Hmgu/Nfatc3tm1b(EUCOMM)Hmgu
C57BL/6N-Nfatc3tm1b(EUCOMM)Hmgu/Ieg
preweaning lethality, complete penetrance J:211773
Nfatc3tm1Glm/Nfatc3tm1Glm
involves: 129S2/SvPas
abnormal skeletal muscle morphology J:68675
decreased embryo size J:50124
decreased extensor digitorum longus weight J:68675
decreased response of heart to induced stress J:79608
decreased skeletal muscle fiber number J:68675
decreased soleus weight J:68675
muscle weakness J:68675
periorbital edema J:50124
prenatal lethality, incomplete penetrance J:50124
Nfatc3tm1Grc/Nfatc3tm1Grc
Not Specified
no abnormal phenotype detected J:141917
Nfatc3tm1Grc/Nfatc3tm1Grc
Tg(Lck-cre)I57Jxm/0
involves: ICR
abnormal T cell differentiation J:141917
decreased CD4-positive, alpha beta T cell number J:141917
decreased CD8-positive, alpha-beta T cell number J:141917
decreased thymocyte number J:141917
increased double-negative T cell number J:141917
increased T cell apoptosis J:141917
lymph node hypoplasia J:141917
thymus hypoplasia J:141917

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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory