Arhgef2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arhgef2
Rho/Rac guanine nucleotide exchange factor 2
MGI:103264

19 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arhgef2^em1(IMPC)Mbp/Arhgef2^em1(IMPC)Mbp C57BL/6N-Arhgef2^em1(IMPC)Mbp/MbpMmucd	abnormal brain morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	decreased brain size	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating serum albumin level	J:211773
	increased circulating total protein level	J:211773
	small liver	J:211773
	small spleen	J:211773
	thrombocytopenia	J:211773
Arhgef2^{Gt(IST13976A8)Tigm}/Arhgef2^{Gt(IST13976A8)Tigm} involves: C57BL/6N	abnormal brainstem morphology	J:242973
	abnormal cerebellum morphology	J:242973
	abnormal macrophage physiology	J:209086
	abnormal neuronal migration	J:242973
	decreased brain size	J:242973
	decreased interferon-beta secretion	J:209086
	normal immune system phenotype	J:209086
	increased susceptibility to Orthomyxoviridae infection	J:209086
	microcephaly	J:242973

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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