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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Vhl
von Hippel-Lindau tumor suppressor
MGI:103223
36 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Arnttm1Bra/Arnttm1Bra
Hprt1tm1(Pck1-cre)Vhh/Y
Vhltm1Jae/Vhltm1Jae
involves: 129 * BALB/c * C57BL/6 		normal hematopoietic system phenotype J:97652
hepatic steatosis J:97652
normal neoplasm J:97652
normal renal/urinary system phenotype J:106705
Arnttm1Bra/Arnttm1Bra
Vhltm1Jae/Vhltm1Jae
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129 * BALB/c * C57BL/6 * DBA 		normal liver/biliary system phenotype J:97652
Epas1tm1Mcs/Epas1tm1Mcs
Hif1atm3Rsjo/Hif1atm3Rsjo
Vhltm1Jae/Vhltm1Jae
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * CD-1 		decreased bone trabecula number J:186085
decreased circulating erythropoietin level J:186085
decreased trabecular bone volume J:186085
normal hematopoietic system phenotype J:186085
Epas1tm1Mcs/Epas1tm1Mcs
Vhltm1Jae/Vhltm1Jae
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: 129S4/SvJae * 129X1/SvJ * CD-1 		decreased circulating erythropoietin level J:186085
normal hematopoietic system phenotype J:186085
Hif1atm1Rsjo/Hif1atm1Rsjo
Hif1antm1.2Rsjo/Hif1antm1.2Rsjo
Vhltm1Jae/Vhltm1Jae
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ 		normal cellular phenotype J:160941
Hif1atm3Rsjo/Hif1atm3Rsjo
Hprt1tm1(Pck1-cre)Vhh/Y
Vhltm1Jae/Vhltm1Jae
involves: 129 * BALB/c * C57BL/6 		abnormal kidney morphology J:106705
abnormal kidney vasculature morphology J:106705
abnormal vasodilation J:97652
hepatic steatosis J:97652
increased hemoglobin content J:97652
increased hepatic hemangioma incidence J:97652
increased vascular endothelial cell number J:97652
kidney cyst J:106705
kidney inflammation J:106705
polycythemia J:97652
Hif1atm3Rsjo/Hif1atm3Rsjo
Vhltm1Jae/Vhltm1Jae
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129 * BALB/c * C57BL/6 * DBA 		abnormal vasodilation J:97652
hepatic steatosis J:97652
increased vascular endothelial cell number J:97652
Hif1atm3Rsjo/Hif1atm3Rsjo
Vhltm1Jae/Vhltm1Jae
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * CD-1 		increased circulating erythropoietin level J:186085
increased hematocrit J:186085
Ptentm1Hwu/Ptentm1Hwu
Vhltm1Jae/Vhltm1Jae
Tg(Cdh16-cre)91Igr/0
involves: 129S4/SvJae * BALB/c * C57BL/6J * ICR 		abnormal kidney cortex morphology J:137073
abnormal kidney epithelium morphology J:137073
abnormal kidney pelvis urothelium morphology J:137073
abnormal renal tubule epithelial cell primary cilium morphology J:137073
hydronephrosis J:137073
increased kidney cell proliferation J:137073
increased kidney weight J:137073
kidney cortex cyst J:137073
kidney cyst J:137073
kidney medulla cyst J:137073
normal neoplasm J:137073
Ptentm1Hwu/Ptentm1Hwu
Vhltm1Jae/Vhltm1Jae
Tg(Cdh16-cre)91Igr/0
involves: 129S4/SvJae * ICR 		abnormal epididymis morphology J:137442
abnormal oviduct morphology J:137442
abnormal uterine cervix squamous epithelium morphology J:137442
endometrium hyperplasia J:137442
increased adenoma incidence J:137442
increased epididymal cystadenoma incidence J:137442
increased tumor incidence J:137442
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory