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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mcm4
minichromosome maintenance complex component 4
MGI:103199
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm4chaos3/Mcm4chaos3
involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J 		abnormal erythrocyte morphology J:165667
abnormal pluripotent precursor cell morphology J:165667
chromosomal instability J:165667
decreased body weight J:165667
decreased fibroblast proliferation J:165667
increased leukemia incidence J:165667
increased T cell derived lymphoma incidence J:165667
increased tumor incidence J:165667
postnatal lethality J:165667
premature death J:165667
reticulocytosis J:165667
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm4Gt(RRE056)Byg/Mcm4+
involves: 129P2/OlaHsd * C3HeB/FeJ 		abnormal erythrocyte morphology J:165667
chromosomal instability J:165667
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm4Gt(RRE056)Byg/Mcm4+
Mcm6Gt(YHD248)Byg/Mcm6+
involves: 129P2/OlaHsd * C3HeB/FeJ 		abnormal erythrocyte morphology J:165667
chromosomal instability J:165667
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4chaos3/Mcm4chaos3
involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J 		abnormal erythrocyte morphology J:165667
abnormal pluripotent precursor cell morphology J:165667
chromosomal instability J:165667
decreased fibroblast proliferation J:165667
normal growth/size/body region phenotype J:165667
normal hematopoietic system phenotype J:165667
increased tumor incidence J:165667
postnatal lethality, incomplete penetrance J:165667
premature death J:165667
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4Gt(RRE056)Byg/Mcm4+
involves: 129P2/OlaHsd * C3HeB/FeJ 		abnormal erythrocyte morphology J:165667
chromosomal instability J:165667
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4Gt(RRE056)Byg/Mcm4+
Mcm6Gt(YHD248)Byg/Mcm6+
involves: 129P2/OlaHsd * C3HeB/FeJ 		abnormal erythrocyte morphology J:165667
chromosomal instability J:165667
Mcm2Gt(AB0178)Wtsi/Mcm2+
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4Gt(RRE056)Byg/Mcm4+
Mcm6Gt(YHD248)Byg/Mcm6+
Mcm7Gt(YTA285)Byg/Mcm7+
involves: 129P2/OlaHsd * C3HeB/FeJ 		abnormal erythrocyte morphology J:165667
chromosomal instability J:165667
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4chaos3/Mcm4chaos3
involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J 		abnormal pluripotent precursor cell morphology J:165667
increased mammary gland tumor incidence J:165667
normal mortality/aging J:165667
normal neoplasm J:165667
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4chaos3/Mcm4chaos3
Mcm6Gt(YHD248)Byg/Mcm6+
involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J 		increased lymphoma incidence J:165667
increased tumor incidence J:165667
postnatal lethality, incomplete penetrance J:165667
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4chaos3/Mcm4Gt(RRE056)Byg
involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J 		increased lymphoma incidence J:165667
increased mammary gland tumor incidence J:165667
postnatal lethality, incomplete penetrance J:165667
premature death J:165667
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4Gt(RRE056)Byg/Mcm4+
involves: 129P2/OlaHsd * C3HeB/FeJ 		abnormal erythrocyte morphology J:165667
chromosomal instability J:165667
Mcm3Gt(RRR002)Byg/Mcm3+
Mcm4Gt(RRE056)Byg/Mcm4+
Mcm6Gt(YHD248)Byg/Mcm6+
involves: 129P2/OlaHsd * C3HeB/FeJ 		abnormal erythrocyte morphology J:165667
chromosomal instability J:165667
Mcm4chaos3/Mcm4chaos3
Mcm6Gt(YHD248)Byg/Mcm6+
involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J 		decreased body weight J:165667
postnatal lethality, incomplete penetrance J:165667
prenatal lethality, incomplete penetrance J:165667
Mcm4chaos3/Mcm4chaos3
Mcm7Gt(YTA285)Byg/Mcm7+
involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J 		abnormal erythrocyte morphology J:165667
chromosomal instability J:165667
decreased body weight J:165667
postnatal lethality, incomplete penetrance J:165667
prenatal lethality, incomplete penetrance J:165667
reticulocytosis J:165667
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory