Mmp7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mmp7
matrix metallopeptidase 7
MGI:103189

20 phenotypes from 1 allele in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mmp7^tm1Lmm/Mmp7^tm1Lmm B6.129-Mmp7^tm1Lmm	abnormal PR interval	J:122893
	abnormal response to cardiac infarction	J:122893
	abnormal sinoatrial node conduction	J:122893
	decreased susceptibility to induced morbidity/mortality	J:122893
	diarrhea	J:149388
	normal digestive/alimentary phenotype	J:149388
	impaired wound healing	J:115243
	increased interleukin-1 beta secretion	J:149388
	increased susceptibility to induced colitis	J:149388
	increased susceptibility to xenobiotic induced morbidity/mortality	J:149388
	increased tumor incidence	J:105098
	intestinal ulcer	J:149388
	weight loss	J:149388
Mmp7^tm1Lmm/Mmp7^tm1Lmm involves: 129S1/Sv * 129X1/SvJ	decreased susceptibility to bacterial infection	J:153651
	decreased susceptibility to injury	J:76811
	normal immune system phenotype	J:55723
Mmp7^tm1Lmm/Mmp7^tm1Lmm involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal induced retina neovascularization	J:119224
Mmp7^tm1Lmm/Mmp7^tm1Lmm involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ	abnormal macrophage physiology	J:124841
	decreased tumor necrosis factor secretion	J:124841
	impaired macrophage chemotaxis	J:124841

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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