Dnase1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dnase1
deoxyribonuclease I
MGI:103157

14 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dnase1^{tm1.1(KOMP)Vlcg}/Dnase1^{tm1.1(KOMP)Vlcg} C57BL/6N-Dnase1^{tm1.1(KOMP)Vlcg}/Tcp	abnormal auditory brainstem response	J:211773
	abnormal heart morphology	J:211773
	abnormal urinary bladder morphology	J:211773
	abnormal uterus morphology	J:211773
	enlarged heart	J:211773
	hydrometra	J:211773
Dnase1^tm2092.1Arte/Dnase1^tm2092.1Arte involves: C57BL/6	abnormal kidney morphology	J:277126
	glomerulonephritis	J:277126
	increased anti-double stranded DNA antibody level	J:277126
	increased anti-histone antibody level	J:277126
	increased anti-nuclear antigen antibody level	J:277126
	increased autoantibody level	J:277126
	increased circulating creatinine level	J:277126
	increased susceptibility to systemic lupus erythematosus	J:277126

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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